Oncology Unit, G. Rummo Hospital, Benevento, Italy.
Hepatol Res. 2007 Sep;37 Suppl 2:S206-9. doi: 10.1111/j.1872-034X.2007.00186.x.
To assess the prognostic ability of the Cancer of the Liver Italian Program (CLIP) score in patients with hepatocellular carcinoma after a longer follow up.
The updated survival data were derived from an analysis that was performed on two joined sets of data. The first set was collected retrospectively in 1995 and was used to perform an exploratory prognostic factor analysis (the CLIP-03 study), that produced the CLIP score. The second set of data was collected prospectively for the CLIP-01 randomized clinical trial.
Out of 912 overall patients, analysis was performed on 650 patients whose records contained all informationregarding prognostic factors. The median survival of the whole group of patients was 17.7 months and the 5-year survival rate was 10.7%. The median survival of the patients was inversely proportional to the CLIP score: the higher the CLIP score the worse the survival.
The CLIP score keeps good prognostic and discriminative abilities after a longer follow up and remains one the most useful prognostic system for hepatocellular carcinoma.
评估癌症意大利计划（CLIP）评分在肝癌患者中的预后能力，随访时间更长。
更新的生存数据来自于对两组联合数据的分析。第一组数据是在 1995 年进行的回顾性收集，用于进行探索性预后因素分析（CLIP-03 研究），产生了 CLIP 评分。第二组数据是为 CLIP-01 随机临床试验前瞻性收集的。
在总共 912 名患者中，对记录中包含所有预后因素信息的 650 名患者进行了分析。整个患者组的中位生存时间为 17.7 个月，5 年生存率为 10.7%。患者的中位生存时间与 CLIP 评分呈反比：CLIP 评分越高，生存越差。
CLIP 评分在更长的随访后仍具有良好的预后和区分能力，是肝癌最有用的预后系统之一。
