一类新的反向信号共刺激分子属于肿瘤坏死因子家族。
A new class of reverse signaling costimulators belongs to the TNF family.
作者信息
Sun Mingyi, Fink Pamela J
机构信息
Department of Immunology, University of Washington, Seattle, WA 98195, USA.
出版信息
J Immunol. 2007 Oct 1;179(7):4307-12. doi: 10.4049/jimmunol.179.7.4307.
PMID:17878324
Abstract
Recent evidence shows that many molecules of the TNF family serve as counter-receptors, inducing costimulation through reverse signals in addition to delivering signals through their respective TNF receptors. In this review, we will discuss this new class of costimulators with a focus on the mechanism of costimulation transduced by reverse signaling through Fas ligand.
摘要
最近的证据表明，许多肿瘤坏死因子（TNF）家族分子可作为反受体，除了通过各自的TNF受体传递信号外，还通过反向信号诱导共刺激。在本综述中，我们将讨论这类新的共刺激分子，重点关注通过Fas配体反向信号传导介导的共刺激机制。
Zotero 插件