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[克罗恩病与癌症风险。发病率/患病率、临床特征及潜在预防策略]

[Crohn's disease and cancer risk. Incidence/prevalence, clinical characteristics, and potential prevention strategies].

作者信息

Allgayer Hubert, Holtmeier Wolfgang, Dietrich Christoph F

机构信息

Schwerpunkt Verdauungs- und Stoffwechselerkrankungen,, Rehaklinik ob der Tauber, Bad Mergentheim, Akademisches Lehrkrankenhaus der Universität Heidelberg.

出版信息

Med Klin (Munich). 2007 Sep 15;102(9):727-33. doi: 10.1007/s00063-007-1091-7.

Abstract

Epidemiologic data concerning the risk for colorectal cancer in ulcerative colitis are based on a variety of large and well-conducted cohort studies. Guidelines for tumor prevention have been published by the German Gastroenterology Society (DGVS) in 2004. By contrast, the risk constellations in Crohn's disease are less clear and guidelines are lacking. Based on a recent literature search (PubMed March 2007), the published data predominantly expressed as relative risk and/or standardized incidence/mortality ratio are critically reviewed with recommendations for tumor prevention strategies based on individual risk constellations.

摘要

有关溃疡性结肠炎患者患结直肠癌风险的流行病学数据,是基于大量精心开展的队列研究得出的。德国胃肠病学会(DGVS)于2004年发布了肿瘤预防指南。相比之下,克罗恩病的风险情况尚不明确,且缺乏相关指南。基于近期的文献检索(2007年3月的PubMed),对主要以相对风险和/或标准化发病率/死亡率比值表示的已发表数据进行了严格审查,并根据个体风险情况提出了肿瘤预防策略的建议。

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