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Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block.
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Hematopoietic stem cell and multilineage defects generated by constitutive beta-catenin activation.
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Hmgb3 regulates the balance between hematopoietic stem cell self-renewal and differentiation.
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Expression of beta-catenin by acute myeloid leukemia cells predicts enhanced clonogenic capacities and poor prognosis.
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Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context.
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Glycogen synthase kinase-3 is an in vivo regulator of hematopoietic stem cell repopulation.
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Wnt signalling in stem cells and cancer.
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Constitutive activation of the Wnt/beta-catenin signalling pathway in acute myeloid leukaemia.
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Integration of Notch and Wnt signaling in hematopoietic stem cell maintenance.
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c-Myc controls the balance between hematopoietic stem cell self-renewal and differentiation.
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