Knoring B E, Kornetova N V, Mitina O F
Probl Tuberk. 1991(10):67-9.
The results of ++clinico-serological examination of 81 subjects with meningeal diseases are given; among them 53 had tuberculous meningitis. The authors applied complement fixation (CFT) and indirect hemagglutination tests (IHT) with tuberculin. The high diagnostic significance of CFT and low efficiency of IHT were established in tuberculous meningitis detection. It is expedient to determine simultaneously the antituberculous antibodies in the blood serum and cerebrospinal fluid of the examined patients. Simultaneous performance of CFT during the follow-up increases its diagnostic potentialities to 88.6%. Detection of complement-binding antibodies only in CFT is, in most cases, a sign of isolated tuberculous meningitis. Detection of specific antibodies only in the blood serum of tuberculous meningitis patients is an indirect evidence of generalized process.
给出了81例脑膜疾病患者的临床血清学检查结果;其中53例患有结核性脑膜炎。作者应用结核菌素补体结合试验(CFT)和间接血凝试验(IHT)。在结核性脑膜炎检测中确定了CFT的高诊断意义和IHT的低效率。同时测定受检患者血清和脑脊液中的抗结核抗体是适宜的。随访期间同时进行CFT可将其诊断潜力提高到88.6%。在大多数情况下,仅在CFT中检测到补体结合抗体是孤立性结核性脑膜炎的迹象。仅在结核性脑膜炎患者血清中检测到特异性抗体是全身性病变的间接证据。