[免疫酶法检测结核性脑膜炎患者脑脊液中的抗结核抗体]
[Determination of antituberculous antibodies in the cerebrospinal fluid by an immunoenzyme assay method in patients with tuberculous meningitis].
作者信息
Tarasova E F, Beresneva R E, Shipina L K, Vladimirskiĭ M A, Kosyreva O A
出版信息
Probl Tuberk. 1990(5):3-5.
PMID:2117752
Abstract
Possibilities of using enzyme immunoassay to identify specific antibodies to M. tuberculosis in the cerebrospinal fluid of 44 patients with tuberculous meningitis and 81 cases with other diseases of the central nervous system were analysed. The assay sensitivity and specificity in an active period of tuberculous meningitis made up 100 and 97.5%, respectively. The findings permit one to recommend the enzyme immunoassay for an early diagnosis of tuberculous meningitis.
摘要
分析了用酶免疫测定法在44例结核性脑膜炎患者及81例其他中枢神经系统疾病患者的脑脊液中鉴定结核分枝杆菌特异性抗体的可能性。在结核性脑膜炎活动期，该测定法的敏感性和特异性分别为100%和97.5%。这些发现使人们可以推荐用酶免疫测定法对结核性脑膜炎进行早期诊断。
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