特应性疾病、免疫系统与环境。

Atopic disease, immune system, and the environment.

作者信息

Leonardi Salvatore, Miraglia del Giudice Michele, La Rosa Mario, Bellanti Joseph A

机构信息

Department of Pediatrics, Catania University, Catania, Italy.

出版信息

Allergy Asthma Proc. 2007 Jul-Aug;28(4):410-7. doi: 10.2500/aap.2007.28.2954.

DOI:10.2500/aap.2007.28.2954

PMID:17883908

Abstract

Raised prevalence of allergic respiratory diseases observed in the last 20 years seems to be associated with changes of environment and lifestyle, which favor a delayed acquisition of Th1 function in childhood. The purpose of this study is to review recent knowledge concerning the developing human immune system and its interaction with external environmental factors for a better understanding of the changing faces of allergic diseases through infancy and childhood in the allergy-prone individual.

摘要

过去20年中观察到的过敏性呼吸道疾病患病率上升，似乎与环境和生活方式的变化有关，这些变化有利于儿童期Th1功能的延迟获得。本研究的目的是回顾有关人类免疫系统发育及其与外部环境因素相互作用的最新知识，以便更好地理解过敏易感个体在婴儿期和儿童期过敏性疾病不断变化的情况。