Shafi Mehnaz A, Pasricha P Jay
University of Texas Medical Branch, 4.106 McCullough Building, 301 University Boulevard, Galveston TX 77555-0764, USA.
Curr Gastroenterol Rep. 2007 Aug;9(4):280-5. doi: 10.1007/s11894-007-0031-2.
Post-surgical gastroparesis (PSG) is recognized as a consequence of vagal nerve injury following upper abdominal surgery. It has been well documented following vagotomy for peptic ulcer surgery. With the increasing role of surgical treatment in the management of GERD and morbid obesity, PSG is now being diagnosed after fundoplication and bariatric surgery. PSG has also been reported after heart and lung transplantation, possibly due to opportunistic viral infection or motor-inhibitory effects of the immunosuppressive drugs, in addition to vagal nerve injury. Initial postoperative management of PSG should be conservative as many symptoms following abdominal surgery resolve with time. This occurs possibly because the enteric nervous system is able to adapt to the loss of vagal input or vagal reinnervation occurs. Persistent symptoms are difficult to manage and require a multidisciplinary team approach. Gastric electrical stimulation has shown promise in small series.
术后胃轻瘫(PSG)被认为是上腹部手术后迷走神经损伤的结果。在消化性溃疡手术的迷走神经切断术后,这一点已有充分记录。随着手术治疗在胃食管反流病(GERD)和病态肥胖管理中作用的增加,现在在胃底折叠术和减肥手术后也能诊断出PSG。在心脏和肺移植后也有PSG的报道,除了迷走神经损伤外,可能还由于机会性病毒感染或免疫抑制药物的运动抑制作用。PSG的术后初始管理应保守,因为腹部手术后的许多症状会随着时间的推移而缓解。这可能是因为肠神经系统能够适应迷走神经输入的丧失或发生迷走神经再支配。持续的症状难以管理,需要多学科团队的方法。胃电刺激在小系列研究中显示出了前景。