Abell Thomas L, Minocha Anil
Division of Digestive Diseases, University of Mississippi Medical Center, Jackson, Mississippi 39216, USA.
Am J Med Sci. 2006 Apr;331(4):214-8. doi: 10.1097/00000441-200604000-00008.
Severe or morbid obesity, with body mass indexes exceeding 35 to 40, are often refractory to all therapies other than surgery. The increasing number of patients undergoing bariatric surgery will result in increasing numbers of patients with gastrointestinal complications. The types of complications vary with type of surgery, whether restrictive, malabsorptive, or both, depending on what anatomical and physiologic changes occur postoperatively. One complication of bariatric surgery (gallstones) is due to weight loss after surgery, not the surgery itself. Based on previous meta-analyses, most of the top 10 complications from bariatric surgery are gastrointestinal: dumping, vitamin/mineral deficiencies, vomiting (and nausea), staple line failure, infection, stenosis (and bowel obstruction), ulceration, bleeding, splenic injury, and perioperative death. Two other gastrointestinal complications of bariatric surgery are indirect consequences of the surgery: bacterial overgrowth and diarrhea. Awareness of the types and frequency of gastrointestinal complications of bariatric surgery allows for timely diagnosis and appropriate therapy. As new surgical, and even endoscopic, procedures to treat obesity are developed, new gastrointestinal complications will need to be recognized.
严重肥胖或病态肥胖,即体重指数超过35至40,通常对手术以外的所有治疗方法都具有难治性。接受减肥手术的患者数量不断增加,将导致胃肠道并发症患者数量增多。并发症的类型因手术类型而异,无论是限制性手术、吸收不良性手术还是两者兼具的手术,这取决于术后发生了哪些解剖学和生理学变化。减肥手术的一种并发症(胆结石)是由术后体重减轻引起的,而非手术本身。根据以往的荟萃分析,减肥手术的十大并发症大多是胃肠道方面的:倾倒综合征、维生素/矿物质缺乏、呕吐(和恶心)、吻合口漏、感染、狭窄(和肠梗阻)、溃疡、出血、脾损伤以及围手术期死亡。减肥手术的另外两种胃肠道并发症是手术的间接后果:细菌过度生长和腹泻。了解减肥手术胃肠道并发症的类型和发生率有助于及时诊断和进行适当治疗。随着治疗肥胖的新手术甚至内镜手术的不断发展,新的胃肠道并发症将需要得到认识。