猫肉瘤中的染色体超二倍体

Chromosomal hyperdiploidy in a feline sarcoma.

作者信息

Kalat M, Mayr B, Schleger W, Wagner B, Reifinger M

机构信息

Ludwig Boltzmann Institute for Immuno- and Cytogenetic Research, Vienna, Austria.

出版信息

Res Vet Sci. 1991 Sep;51(2):227-8. doi: 10.1016/0034-5288(91)90019-k.

DOI:10.1016/0034-5288(91)90019-k

PMID:1788488

Abstract

An eight-year-old male cat developed a sarcoma. The cytogenetic evaluation of the tumour cells showed the presence of hyperdiploidy (range 40 to 46 chromosomes). This hyperdiploidy was encountered in all the cells examined. Extra-chromosomes numbers C1, C2, B4, D4 and E3 were mainly responsible for the hyperdiploid chromosomal complements. There was a high incidence of monosomy E3.

摘要

一只八岁的雄性猫患上了肉瘤。对肿瘤细胞的细胞遗传学评估显示存在超二倍体（染色体数范围为40至46条）。在所检查的所有细胞中均发现了这种超二倍体。额外的染色体编号C1、C2、B4、D4和E3是超二倍体染色体组型的主要原因。E3单体的发生率很高。