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冠状动脉扩张的临床表现。

Clinical expression of coronary artery ectasia.

作者信息

Valente Serafina, Lazzeri Chiara, Giglioli Cristina, Sani Francesca, Romano Salvatore Mario, Margheri Massimo, Comeglio Marco, Gensini Gian Franco

机构信息

Heart and Vessel Department, Azienda Ospedaliero--Universitaria Careggi, University of Florence, School of Medicine, Florence, Italy.

出版信息

J Cardiovasc Med (Hagerstown). 2007 Oct;8(10):815-20. doi: 10.2459/JCM.0b013e3280115667.

Abstract

OBJECTIVE

Coronary artery ectasia (CAE) is an uncommon finding at cardiac catheterisation. Our objective was to retrospectively assess the angiographic prevalence of CAE and its clinical expression.

METHODS

From January 1999 to June 2001, 3870 consecutive patients underwent coronary angiography at our catheterisation laboratory.

RESULTS

The prevalence of CAE was 3.6%. Most patients were male (89.2%). Type 1 CAE was observed in 20% of patients, type 2 in 11%, type 3 in 43%, and type 4 in 26%. The right coronary artery was most commonly involved (75%). In 55 patients with acute myocardial infarction, CAE within the culprit vessel was found in 32 patients (58.1%): ectasia was associated with stenosis in 29 patients, whereas isolated CAE was observed in only three patients. In 23 patients (41.8%), CAE was detected as a collateral finding in the presence of the culprit occluded, non-ectatic vessel. Overall, in the 109 patients (78%) with acute coronary syndrome, the culprit lesion was found to be related to the ectatic vessel in 46 patients (33.1%): ectasia was associated with stenosis in 39 patients, whereas isolated CAE was observed in only seven patients. In 66.9% CAE was an incidental finding on angiography. At follow-up, three patients with CAE died (2%).

CONCLUSIONS

In our investigation, the angiographic prevalence of CAE was 3.6%. CAE occurred predominantly in males and more often affected the right coronary artery. It was associated with acute coronary syndrome in one third of cases. Isolated CAE was associated with a good prognosis at follow-up.

摘要

目的

冠状动脉扩张(CAE)是心脏导管检查中不常见的发现。我们的目的是回顾性评估CAE的血管造影患病率及其临床表现。

方法

1999年1月至2001年6月,连续3870例患者在我们的导管实验室接受冠状动脉造影。

结果

CAE的患病率为3.6%。大多数患者为男性(89.2%)。20%的患者观察到1型CAE,11%为2型,43%为3型,26%为4型。右冠状动脉最常受累(75%)。在55例急性心肌梗死患者中,32例(58.1%)在罪犯血管内发现CAE:29例患者的扩张与狭窄相关,而仅3例患者观察到孤立性CAE。在23例患者(41.8%)中,在罪犯闭塞、非扩张血管存在的情况下,CAE作为附带发现被检测到。总体而言,在109例急性冠状动脉综合征患者(78%)中,46例患者(33.1%)的罪犯病变被发现与扩张血管有关:39例患者的扩张与狭窄相关,而仅7例患者观察到孤立性CAE。66.9%的CAE是血管造影时的偶然发现。随访时,3例CAE患者死亡(2%)。

结论

在我们的研究中,CAE的血管造影患病率为3.6%。CAE主要发生在男性,更常累及右冠状动脉。三分之一的病例与急性冠状动脉综合征相关。孤立性CAE在随访中预后良好。

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