Yao Yi-an, Zhang Shu-yang, Wu Wei, Chen Lian-feng
Department of Cardiology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.
Zhonghua Nei Ke Za Zhi. 2010 May;49(5):389-91.
To retrospectively analyze the clinical manifestations of coronary artery ectasia and its angiographic characteristics.
Twenty-five patients who underwent coronary angiography were diagnosed as coronary artery ectasia from January 2005 to December 2007. 25 cases of coronary artery atherosclerosis were also included and 25 cases with normal coronary arteriography in the same period were taken as control.
Most of the patients were male (72%). Only three patients had diabetes and thirteen patients had hypertension. All the patients with coronary artery ectasia were admitted for chest pain. Nine of them showed abnormal ST changes and four elevated ST in ECG. Coronary artery ectasia was associated with slow coronary flow in 9 patients and coronary stenosis in 4 patients. The frequency of arterial involvement, in descending order, was right coronary artery in 76%, left anterior descending artery in 60%, left circumflex artery in 48% and left main artery in 8%. Ectasia affected only one major vessel was found in 44%, and all three vessels in 36%. As compared with the patients with coronary artery atherosclerosis and patients with normal coronary artery, patients with CAE had a lower prevalence of diabetes (12%), and there were no other significant statistics in clinical demography and other risk factors such as hypertension and dyslipidemia.
Coronary artery ectasia was prevalent in males and diabetes was less frequent. The RCA was the most commonly affected vessel and most of the patients had single vessel involvement.
回顾性分析冠状动脉扩张的临床表现及其血管造影特征。
选取2005年1月至2007年12月期间接受冠状动脉造影并被诊断为冠状动脉扩张的25例患者。另纳入25例冠状动脉粥样硬化患者,并选取同期25例冠状动脉造影正常的患者作为对照。
大多数患者为男性(72%)。仅有3例患者患有糖尿病,13例患者患有高血压。所有冠状动脉扩张患者均因胸痛入院。其中9例心电图ST段改变异常,4例ST段抬高。9例冠状动脉扩张患者伴有冠状动脉血流缓慢,4例伴有冠状动脉狭窄。动脉受累频率由高到低依次为:右冠状动脉76%,左前降支60%,左旋支48%,左主干8%。44%的患者仅1支主要血管受累,36%的患者3支血管均受累。与冠状动脉粥样硬化患者和冠状动脉正常患者相比,冠状动脉扩张患者糖尿病患病率较低(12%),在临床人口统计学及高血压、血脂异常等其他危险因素方面无其他显著统计学差异。
冠状动脉扩张在男性中较为普遍,糖尿病患者较少见。右冠状动脉是最常受累的血管,大多数患者为单支血管受累。