来自大阳瓜品种南瓜果实的葫芦烷型和降葫芦烷型糖苷。

Cucurbitane and hexanorcucurbitane glycosides from the fruits of Cucurbita pepo cv dayangua.

作者信息

Wang Da-Cheng, Pan Hong-Yu, Deng Xu-Ming, Xiang Hua, Gao Hui-Yuan, Cai Hui, Wu Li-Jun

机构信息

School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shengyang, China.

出版信息

J Asian Nat Prod Res. 2007 Sep-Dec;9(6-8):525-9. doi: 10.1080/10286020600782538.

DOI:10.1080/10286020600782538

PMID:17885839

Abstract

Phytochemical investigation of the fruits of Cucurbita pepo cv dayangua has led to the isolation of two cucurbitane glycosides: cucurbitacin L 2-O-beta-D-glucopyranoside (1), cucurbitacin K 2-O-beta-D-glucopyranoside (2) and two hexanorcucurbitane glycosides: 2,16-dihydroxy-22,23,24,25,26,27-hexanorcucurbit-5-en-11,20-dione 2-O-beta-D-glucopyranoside (3) and 16-hydroxy-22,23,24,25,26,27-hexanorcucurbit-5-en-11,20-dione 3-O-alpha-L-rhamnopyranosyl-(1 --> 2)-beta-D-glucopyranoside (4). Compounds 1, 2 and 3 were isolated from Cucurbita genus for the first time, while compound 4 is a new one. Their structures were determined on the basis of chemical and spectroscopic evidence.

摘要

对“大洋瓜”南瓜品种果实进行植物化学研究，从中分离出两种葫芦烷糖苷：葫芦素L 2-O-β-D-吡喃葡萄糖苷（1）、葫芦素K 2-O-β-D-吡喃葡萄糖苷（2），以及两种六降葫芦烷糖苷：2,16-二羟基-22,23,24,25,26,27-六降葫芦-5-烯-11,20-二酮2-O-β-D-吡喃葡萄糖苷（3）和16-羟基-22,23,24,25,26,27-六降葫芦-5-烯-11,20-二酮3-O-α-L-鼠李吡喃糖基-(1→2)-β-D-吡喃葡萄糖苷（4）。化合物1、2和3首次从南瓜属植物中分离得到，而化合物4是新化合物。它们的结构是根据化学和光谱证据确定的。