来自苦瓜果实的葫芦烷型三萜糖苷。

Cucurbitane-type triterpene glycosides from the fruits of Momordica charantia.

作者信息

Liu Yi, Ali Zulfiqar, Khan Ikhlas A

机构信息

National Center for Natural Products Research, School of Pharmacy, University of Mississippi, University, Mississippi, USA.

出版信息

Planta Med. 2008 Aug;74(10):1291-4. doi: 10.1055/s-2008-1081297. Epub 2008 Jul 11.

DOI:10.1055/s-2008-1081297

PMID:18622906

Abstract

Phytochemical investigation of the fruits of Momordica charantia resulted in the isolation and characterization of two new (1 and 2) and eight known cucurbitane-type triterpene glycosides and one cucurbitane-type triterpene. The glycosides (7beta,25-dimethoxycucurbita-5(6),23( E)-dien-19-al 3- O-beta-D-allopyranoside (1); 25-methoxycucurbita-5(6),23(E)-dien-19-ol 3-O-beta-D-allopyranoside (2); momordicosides A, F (1), F (2), G, K, and L; and goyaglycoside-c and goyaglycoside-d) and the triterpene [3 beta,7 beta,25-trihydroxycucurbita-5,23(E)-dien-19-al] were characterized by physical, chemical, and spectroscopic techniques, including 1D- and 2D-NMR as well as by comparison with the reported data.

摘要

对苦瓜果实进行植物化学研究，从中分离并鉴定出两种新的（1和2）以及八种已知的葫芦烷型三萜糖苷和一种葫芦烷型三萜。通过物理、化学和光谱技术，包括一维和二维核磁共振，以及与已报道数据进行比较，对糖苷（7β,25 - 二甲氧基葫芦巴 - 5(6),23(E) - 二烯 - 19 - 醛3 - O - β - D - 阿洛吡喃糖苷（1）；25 - 甲氧基葫芦巴 - 5(6),23(E) - 二烯 - 19 - 醇3 - O - β - D - 阿洛吡喃糖苷（2）；苦瓜皂苷A、F（1）、F（2）、G、K和L；以及戈亚糖苷 - c和戈亚糖苷 - d）和三萜[3β,7β,25 - 三羟基葫芦巴 - 5,23(E) - 二烯 - 19 - 醛]进行了表征。