Korytova L I, Il'in N V, Kaganskiĭ V L
Ter Arkh. 1991;63(7):44-7.
Systemic radiotherapy in the form of subtotal radiation of the body (STRB) was provided for the first time to 23 patients with lymphogranulomatosis, stages IIIB-IVB, as the first stage of anticancer treatment as an alternative to chemotherapy. STRB was established to produce marked immediate and steady anticancer effects manifesting in the removal of intoxication, a reduction of the size of the lymph nodes and specific infiltration in the lungs, and the lowering of the ESR. The duration of STRB was 10.6 days on the average, with the interval till the next treatment stage amounting to 31.2 days. The regularities were established in the time-course of changes in the hematological parameters in the course of and after STRB, permitting one to define them as a subacute radiation syndrome.
作为抗癌治疗的第一阶段,首次对23例ⅢB - ⅣB期淋巴肉芽肿病患者采用全身局部照射(STRB)形式的全身放疗替代化疗。采用STRB是为了产生显著的即刻和稳定的抗癌效果,表现为消除中毒症状、缩小淋巴结大小以及减轻肺部的特异性浸润,并降低血沉。STRB的持续时间平均为10.6天,直至下一治疗阶段的间隔时间为31.2天。确定了STRB期间及之后血液学参数变化的时间进程规律,从而可以将其定义为亚急性放射综合征。