在感染劳斯肉瘤病毒布莱恩高滴度株的日本鹌鹑胚胎细胞系中进行的病毒糖蛋白合成研究。
Viral glycoprotein synthesis studies in an established line of Japanese quail embryo cells infected with the Bryan high-titer strain of Rous sarcoma virus.
作者信息
Halpern M S, Bolognesi D P, Friis R R
出版信息
J Virol. 1976 May;18(2):504-10. doi: 10.1128/JVI.18.2.504-510.1976.
Abstract
Although a glycoprotein with an approximate molecular weight of 43,000 is associated with purified virions of the Bryan high-titer strain of Rous sarcoma virus propagated on R(-)Q cells, these virions lack gp85, the major glycoprotein of the avian tumor virus envelope. As measured by immune precipitation with a specific antiserum, gp85 does not accumulate to detectable levels in R(-)Q cells.
摘要
虽然一种分子量约为43,000的糖蛋白与在R(-)Q细胞上繁殖的劳斯肉瘤病毒Bryan高滴度株的纯化病毒粒子相关联，但这些病毒粒子缺乏禽肿瘤病毒包膜的主要糖蛋白gp85。用特异性抗血清进行免疫沉淀测定时，gp85在R(-)Q细胞中不会积累到可检测的水平。
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