Rambeck W A, Brehm H W, Kollmer W E
Institut für Physiologie, Physiologische Chemie und Ernährungsphysiologie, Tierärztlichen Fakultät, LMU München.
Z Ernahrungswiss. 1991 Dec;30(4):298-306. doi: 10.1007/BF01651959.
In commercial pig fattening copper is added to the feed at a concentration exceeding the requirement by a factor of more than ten. This improves the weight gain of the pigs during the first three months remarkably. In order to study the influence of copper supplementation on cadmium retention, 4 groups of male castrated weanling crossbred pigs (Deutsche Landrasse x Pietrain) received for 3 months a diet containing 1 mg Cd per kg feed, given as CdCl2, as well as 0, 50, 100 or 200 mg Cu per kg feed, given as CuSO4. The liver, kidney, spleen, pancreas, brain, heart, diaphragm, bile and duodenal mucosa were submitted to wet ashing and analyzed by atomic absorption spectroscopy for cadmium. The Cd retention in all tissues increased in correlation to the Cu content of the feed. When 200 mg Cu per kg were added, Cd rose in the muscle from 10 to 15 micrograms per kg, in the liver from 770 to 1720 micrograms per kg and in the kidney, where the highest Cd concentration occurred, from 4620 to 9320 micrograms per kg. This indicates that in pigs the retention of cadmium in kidney and in liver is promoted by Cu supplementation as used in commercial pig fattening.
在商业性生猪育肥过程中,铜以超过需求十多倍的浓度添加到饲料中。这显著提高了猪在前三个月的体重增加量。为了研究补充铜对镉潴留的影响,4组雄性去势断奶杂交猪(德国长白猪×皮特兰猪)连续3个月食用每千克饲料含1毫克镉(以氯化镉形式提供)以及每千克饲料含0、50、100或200毫克铜(以硫酸铜形式提供)的日粮。将肝脏、肾脏、脾脏、胰腺、大脑、心脏、横膈膜、胆汁和十二指肠黏膜进行湿式灰化处理,并通过原子吸收光谱法分析镉含量。所有组织中的镉潴留量与饲料中的铜含量呈正相关。当每千克添加200毫克铜时,肌肉中的镉含量从每千克10微克升至15微克,肝脏中的镉含量从每千克770微克升至1720微克,而在镉浓度最高的肾脏中,镉含量从每千克4620微克升至9320微克。这表明,在生猪育肥中所采用的补充铜的做法会促进猪肾脏和肝脏中镉的潴留。