Lomuscio A, Castagnone M, Vergani D, Verzoni A, Beltrami A, Ravaglia R, Pozzoni L
Divisione di Cardiologia, Ospedale San Paolo, Milano, Italy.
Acta Cardiol. 1991;46(5):543-54.
We have studied 130 patients with diabetes mellitus and 455 patients without. All the patients were consecutively admitted to our Coronary Care Unit with their first myocardial infarction. We have observed a higher incidence of heart failure, in-hospital mortality, atrial fibrillation, conduction abnormalities, and post-infarction angina among diabetics. Nevertheless, diabetic patients do not show evidence of larger infarcts than those without diabetes. In our patients the higher mortality among diabetics is related to an increased occurrence of left ventricular failure. Moreover, post-infarction ischemic episodes are more common compared with non diabetics. Since infarcts in diabetics do not seem to be more extensive than in non diabetics, we suggest, in accordance with others, that the poorer outcome among diabetic patients with AMI could be related to an underlying cardiac dysfunction of diabetics in addition to coronary artery diseases.
我们研究了130例糖尿病患者和455例非糖尿病患者。所有患者均因首次心肌梗死连续入住我们的冠心病监护病房。我们观察到糖尿病患者中心力衰竭、住院死亡率、房颤、传导异常和梗死后心绞痛的发生率较高。然而,糖尿病患者的梗死面积并不比非糖尿病患者大。在我们的患者中,糖尿病患者较高的死亡率与左心室衰竭发生率增加有关。此外,与非糖尿病患者相比,梗死后缺血发作更常见。由于糖尿病患者的梗死面积似乎并不比非糖尿病患者更广泛,我们与其他人一致认为,急性心肌梗死糖尿病患者预后较差可能与糖尿病患者除冠状动脉疾病外潜在的心脏功能障碍有关。