Basarakodu Krishnamohan R, Aronow Wilbert S, Nair Chandra K, Lakkireddy Dhanunjaya, Kondur Ashok, Korlakunta Hema, Valasareddi Sri Laxmi, Lem Vincent, Schuller Dan
Department of Medicine, Alegent Health Mercy Hospital, Council Bluffs, IA, USA.
Am J Ther. 2007 Sep-Oct;14(5):422-6. doi: 10.1097/01.pap.0000249905.63211.a1.
Organizing pneumonia is a major reparative response of the lung tissue to an acute injury and is a pathological hallmark of an entity called bronchiolitis obliterans organizing pneumonia (BOOP). It can be idiopathic and called cryptogenic organizing pneumonia (COP) or be secondary to various conditions such as infections, drugs, connective tissue disorders, and radiation. Fifty-seven patients with pathologically confirmed BOOP were identified and were classified as having either COP or secondary BOOP on the basis of whether there was an identifiable cause. The two groups were compared for demographic, clinical, laboratory, radiological and treatment variables. Duration of treatment with corticosteroids was longer for patients with COP.
机化性肺炎是肺组织对急性损伤的一种主要修复反应，是闭塞性细支气管炎伴机化性肺炎（BOOP）这一实体的病理标志。它可以是特发性的，称为隐源性机化性肺炎（COP），也可以继发于各种情况，如感染、药物、结缔组织疾病和放疗。确定了57例经病理证实为BOOP的患者，并根据是否有可识别的病因将其分为COP或继发性BOOP。比较了两组患者的人口统计学、临床、实验室、影像学和治疗变量。COP患者使用皮质类固醇的治疗时间更长。
