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蛋白C和蛋白S缺乏患者巨大心脏血栓的治疗

Treatment of massive cardiac thrombi in a patient with protein C and protein S deficiency.

作者信息

Paç F Ayşenur, Cağdaş Deniz N

机构信息

Yuksek Ihtisas Education and Research Hospital, Section of Pediatric Cardiology, Ankara, Turkey.

出版信息

Blood Coagul Fibrinolysis. 2007 Oct;18(7):699-702. doi: 10.1097/MBC.0b013e3282eff788.

DOI:10.1097/MBC.0b013e3282eff788
PMID:17890961
Abstract

Myocarditis and dilated cardiomyopathy is characterized by dilatation of all four cardiac chambers and decreased systolic function of the heart, especially in the left ventricle. In this report we presented a patient with myocarditis or dilated cardiomyopathy and deficiency of protein C and protein S with biventricular multiple intracardiac thrombi. Standard heparin infusion and acetyl salicylic acid was begun. On the 10th day of hospitalization the right ventricular thrombus disappeared, and on the 24th day all thrombi in the left ventricle disappeared. During the treatment we did not observe any complication such as hemorrhagia or embolism. We think that patients with dilated cardiomyopathy or myocarditis should be evaluated for hemostatic disorders, and should be anticoagulated if any of these disorders are presented.

摘要

心肌炎和扩张型心肌病的特征是心脏四个腔室均扩张,心脏收缩功能下降,尤其是左心室。在本报告中,我们介绍了一名患有心肌炎或扩张型心肌病且蛋白C和蛋白S缺乏并伴有双心室多发心内血栓形成的患者。开始标准肝素输注和阿司匹林治疗。住院第10天时右心室血栓消失,第24天时左心室所有血栓均消失。治疗期间,我们未观察到任何出血或栓塞等并发症。我们认为,对于扩张型心肌病或心肌炎患者,应评估其止血障碍情况,若出现任何此类障碍,应进行抗凝治疗。

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Cureus. 2023 Jan 20;15(1):e34012. doi: 10.7759/cureus.34012. eCollection 2023 Jan.
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Congenital Thrombophilia and Intracardiac Thrombosis: Probably an Underdiagnosed Event.先天性血栓形成倾向与心内血栓形成:可能是一种诊断不足的情况。
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Large Left Ventricular Thrombus in a Patient with Systemic and Venous Thromboembolism Secondary to Protein C and S Deficiency.一名继发于蛋白C和S缺乏的系统性及静脉血栓栓塞患者出现左心室巨大血栓。
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