Semenza Gregg L
Vascular Biology Program, Institute for Cell Engineering; Department of Pediatrics, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.
J Cell Biochem. 2007 Nov 1;102(4):840-7. doi: 10.1002/jcb.21523.
In this review, the concept of oxygen homeostasis will be presented as an organizing principle for discussion of the phylogeny, ontogeny, physiology, and pathology of blood vessel formation and remodeling, with a focus on molecular mechanisms and potential therapeutic applications.
在本综述中,氧稳态的概念将作为一个组织原则,用于讨论血管形成和重塑的系统发育、个体发育、生理学和病理学,重点是分子机制和潜在的治疗应用。