McLellan Tom M, Kamimori Gary H, Voss David M, Tate Charmaine, Smith Sarah J R
Individual Readiness Section, DRDC-Toronto, 1133 Sheppard Avenue West, PO Box 2000, Toronto, Ontario M3M 3B9, Canada.
Aviat Space Environ Med. 2007 Sep;78(9):871-7.
This study examined caffeine (CAF) effects on physical performance and vigilance during 4 d and 3 nights of sustained operations in Special Forces personnel.
There were 20 soldiers (28.6 +/- 4.7 yr, 177.6 +/- 7.5 cm, 81.2 +/- 8.0 kg) who were divided equally into placebo (PLAC) and CAF groups. A 4-km run that included three obstacles (OBST) was completed each morning with the performance on Day 2 representing control (CON) after familiarization on Day 1 and an 8-h sleep. From 01:30 to 06:15 of Days 3-5, soldiers performed two 2-h vigilance (VIG) sessions in the field. PLAC or 200 mg of CAF was administered at 21:45 of Days 2-4 and at 01:00, 03:45, and approximately 07:00 on Days 3-5. The run commenced within 30 min of the final dose. Soldiers were provided a 4-h sleep period from 13:30-17:30 during Days 3 and 4.
VIC during Days 3-5 was greater for CAF vs. PLAC and not different from CON. Total run time was faster for CAF (29.7 +/- 2.0 min) compared with PLAC (30.7 +/- 2.9 min) on Day 3 due to faster completion of OBST (8.7 +/- 0.7 min vs. 9.2 +/- 1.0 min for CAF and PLAC, respectively). Thereafter, run times decreased for both groups on Days 4 and 5 compared with CON due primarily to an increased pace between OBST.
it was concluded that CAF maintained both vigilance and physical performance during sustained operations that require periods of overnight wakefulness and restricted opportunities for daytime sleep.
本研究调查了咖啡因(CAF)对特种部队人员持续行动4天3夜期间身体机能和警觉性的影响。
20名士兵(年龄28.6±4.7岁,身高177.6±7.5厘米,体重81.2±8.0千克)被平均分为安慰剂(PLAC)组和CAF组。每天早晨进行一次包含三个障碍物(OBST)的4公里跑步,第2天的表现代表在第1天熟悉和8小时睡眠后的对照(CON)。在第3至5天的01:30至06:15,士兵们在野外进行了两次2小时的警觉性(VIG)测试。在第2至4天的21:45以及第3至5天的01:00、03:45和大约07:00给予PLAC或200毫克CAF。跑步在最后一剂药物后的30分钟内开始。在第3天和第4天,士兵们在13:30至17:30有4小时的睡眠时间。
在第3至5天,CAF组的VIC高于PLAC组,且与CON组无差异。在第3天,CAF组的总跑步时间(29.7±2.0分钟)比PLAC组(30.7±2.9分钟)快,这是因为CAF组完成OBST的速度更快(CAF组和PLAC组分别为8.7±0.7分钟和9.2±1.0分钟)。此后,与CON组相比,两组在第4天和第5天的跑步时间均减少,这主要是由于OBST之间的速度加快。
得出的结论是,在需要夜间清醒且白天睡眠机会受限的持续行动中,CAF可维持警觉性和身体机能。