使用HRT II Rostock角膜模块对一例角膜中氯丙嗪沉积物进行的体内观察。
In vivo observations of a case of chlorpromazine deposits in the cornea using an HRT II Rostock corneal module.
作者信息
Toshida Hiroshi, Uesugi Yuko, Ebihara Nobuyuki, Murakami Akira
机构信息
Department of Ophthalmology, Juntendo University School of Medicine, Tokyo, Japan.
出版信息
Cornea. 2007 Oct;26(9):1141-3. doi: 10.1097/ICO.0b013e318124a42b.
PURPOSE
In vivo study of corneal deposits in a patient receiving chlorpromazine therapy was done by using a confocal microscope, the HRT II Rostock corneal module (RCM).
METHODS
A 23-year-old woman who had been on chlorpromazine therapy for 5 years complained of bilateral photophobia and was referred to our clinic. She had suffered from light sensitivity for 4 years.
RESULTS
Slit-lamp microscopy revealed white deposits, particularly in the layers of the endothelium and Descemet membrane, which were concentrated in the center of both corneas. Deposition of many white granules was observed in the superficial subepithelial stroma of the cornea by HRT II RCM. Granular deposits were observed at the center of most cells in the corneal endothelium.
CONCLUSIONS
The HRT II RCM could clearly detect deposits in the corneal endothelium, as well as in other regions such as the corneal epithelium and stroma.
目的
使用共聚焦显微镜——HRT II罗斯托克角膜模块（RCM），对一名接受氯丙嗪治疗的患者角膜沉积物进行体内研究。
方法
一名23岁女性，接受氯丙嗪治疗5年，主诉双眼畏光，被转诊至我院。她有4年的光敏感病史。
结果
裂隙灯显微镜检查发现白色沉积物，尤其在内皮层和后弹力层，集中在双眼角膜中央。通过HRT II RCM观察到角膜浅表层上皮下基质中有许多白色颗粒沉积。在角膜内皮细胞的大多数细胞中央观察到颗粒状沉积物。
结论
HRT II RCM能够清晰检测角膜内皮以及角膜上皮和基质等其他区域的沉积物。
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