得克萨斯刺萼龙葵地上部分的黄酮类化合物、香豆素和三萜类化合物。

Flavonoids, coumarins and triterpenes from the aerial parts of Cnidoscolus texanus.

作者信息

Yuan Wei, Li Shiyou, Ownby Stacy, Zhang Zhizhen, Wang Ping, Zhang Wanli, Beasley R Scott

机构信息

National Center for Pharmaceutical Crops, Arthur Temple College of Forestry and Agriculture, Stephen F. Austin State University, Nacogdoches, Texas 75965-6109, USA.

出版信息

Planta Med. 2007 Oct;73(12):1304-8. doi: 10.1055/s-2007-990226. Epub 2007 Sep 24.

DOI:10.1055/s-2007-990226

PMID:17893826

Abstract

Phytochemical investigation on Cnidoscolus texanus led to the isolation of 26 compounds, which included 15 flavonoids (1-15), three coumarins (16-18), three coumaric acid derivatives (19-21), four triterpenoids (22-25), and one phytosterol (26). Among them, aromadendrin 7-O-(4''-O-P-E-coumaroyl-beta-glucopyranoside) (1), aromadendrin 7-O-(3'',6''-di-O-P-E-coumaroyl-beta-glucopyranoside) (2), and naringenin 7-O-(4''-O-P-Z-coumaroyl-beta-glucopyranoside) (3) are new compounds. Their structures were determined by spectroscopic and chemical methods. All flavonoids were found to be inactive against DNA topoisomerase I.

摘要

对德克萨斯刺荨麻进行植物化学研究，分离出26种化合物，其中包括15种黄酮类化合物（1 - 15）、3种香豆素（16 - 18）、3种香豆酸衍生物（19 - 21）、4种三萜类化合物（22 - 25）和1种植物甾醇（26）。其中，芳樟醇7 - O -（4'' - O - P - E - 香豆酰基 - β - 葡萄糖苷）（1）、芳樟醇7 - O -（3''，6'' - 二 - O - P - E - 香豆酰基 - β - 葡萄糖苷）（2）和柚皮素7 - O -（4'' - O - P - Z - 香豆酰基 - β - 葡萄糖苷）（3）为新化合物。通过光谱和化学方法确定了它们的结构。所有黄酮类化合物均被发现对DNA拓扑异构酶I无活性。