Instituto de Pesquisas de Produtos Naturais "Walter Mors", Centro de Ciencas da Saude, Universidade Federal do Rio de Janeiro (UFRJ), Avenida Carlos Chagas Filho, 373, Bloco H, Cidade Universitaria, CEP 21941-902, Rio de Janeiro, Brazil.
Instituto Federal de Rondônia, Campus de Ji-Parana, Rua Rio Amazonas, 151, Jardim dos Migrantes, CEP 78960-000, Ji-Paraná-RO, Brazil.
Molecules. 2021 Feb 9;26(4):925. doi: 10.3390/molecules26040925.
(Pax & K. Hoffm.) Ducke (Euphorbiaceae) is a singular species in the genus and is restricted and exclusive to the Brazilian Amazon. A phytochemical study of leaves was performed, yielding the isolation of five major compounds: catechin/epicatechin, afzelin, quercetin 3--α-L-rhamnopyranoside, and astilbin. The phytochemical compositions of the methanolic extracts of leaves, roots, bark, and stem bark were determined using a dereplication approach. Forty-six compounds were annotated from the liquid chromatography-mass spectrometry (LC-MS/MS) data, while four lipids were identified using gas chromatography-mass spectrometry (GC-MS). In total, fifty compounds were detected, and they belonged to the primary metabolism and several classes of natural products such as flavonoids, flavonoids -glycosides, flavonoids -glycosides, biflavonoids, procyanidin, triterpene, triterpenes esterified with phenylpropanoids, phenylpropanoid derivatives, flavonolignans, coumarins, quinic acid derivatives, and benzoic acid derivatives. This is the first report on the phytochemical data of the genus , and the results of this study will contribute to the chemosystematic knowledge of the Euphorbiaceae family and justify the need for investigation of the pharmacological potential of the species .
(Pax & K. Hoffm.) Ducke（大戟科）是该属中的一个独特物种，仅局限于分布在巴西亚马逊地区。对其叶进行了植物化学研究，分离得到了五个主要化合物：儿茶素/表儿茶素、杨梅素、槲皮素 3--α-L-鼠李吡喃糖苷和 astilbin。采用去重复方法确定了叶、根、树皮和茎皮的甲醇提取物的植物化学成分。从液相色谱-质谱联用（LC-MS/MS）数据中注释了 46 种化合物，而使用气相色谱-质谱联用（GC-MS）鉴定了 4 种脂质。总共检测到 50 种化合物，它们属于初级代谢物和几类天然产物，如类黄酮、类黄酮糖苷、类黄酮糖苷、双黄酮、原花青素、三萜、苯丙素酯化的三萜、苯丙素衍生物、黄酮木脂素、香豆素、奎宁酸衍生物和苯甲酸衍生物。这是对属植物化学数据的首次报道，本研究的结果将有助于大戟科的化学系统发育知识，并证明有必要对该物种的药理潜力进行研究。
