Mao Hui, Polensek Sharon H, Goldstein Felicia C, Holder Chad A, Ni Chunchun
Department of Radiology, Emory University School of Medicine, Atlanta, Georgia 30322, USA.
J Neuroimaging. 2007 Oct;17(4):292-4. doi: 10.1111/j.1552-6569.2007.00146.x.
Diffuse axonal injury (DAI) is a common aftermath of brain trauma. The diagnosis of DAI is often difficult using conventional magnetic resonance imaging (MRI). We report a diffusion tensor imaging (DTI) study of a patient who sustained DAI presenting with language impairment. Fractional anisotropy (FA) and DTI tractography revealed a reduction of white matter integrity in the left frontal and medial temporal areas. White matter damage identified by DTI was correlated with the patient's language impairment as assessed by functional MRI (fMRI) and a neuropsychological exam. The findings demonstrate the utility of DTI for identifying white matter changes secondary to traumatic brain injury (TBI).
弥漫性轴索损伤（DAI）是脑外伤常见的后遗症。使用传统磁共振成像（MRI）通常很难诊断DAI。我们报告了一项对一名患有DAI并伴有语言障碍患者的扩散张量成像（DTI）研究。分数各向异性（FA）和DTI纤维束成像显示左额叶和颞内侧区域的白质完整性降低。DTI识别出的白质损伤与通过功能磁共振成像（fMRI）和神经心理学检查评估的患者语言障碍相关。这些发现证明了DTI在识别创伤性脑损伤（TBI）继发的白质变化方面的实用性。
