Kiratli Hayyam, Kocabeyoğlu Sibel, Sağlam Arzu, Söylemezoğlu Figen
Ocular Oncology Service, Department of Ophthalmology, Hacettepe University School of Medicine, Ankara, Turkey.
Clin Exp Ophthalmol. 2007 Sep-Oct;35(7):661-3. doi: 10.1111/j.1442-9071.2007.01567.x.
A 37-year-old man presented with the complaint of a small non-tender mass growing steadily on the left caruncle for 3 months. This was a soft, reddish-yellow tumour, occupying the whole left caruncular area without impinging on the conjunctiva. Histopathological evaluation of the excisional biopsy specimen showed that the tumour was largely composed of Langerhans cells mixed with eosinophils and mature lymphocytes. There were strong CD1a and S-100 positivity on immunohistochemical studies. Langerhans cell histiocytosis is an exceedingly rare tumour of the caruncle in the adult and this lesion cannot be distinguished from other amelanotic lesions on clinical grounds alone. Simple excision of the lesion provided a 4-year disease-free period.
一名37岁男性主诉左侧泪阜有一个无痛性小结节，持续增大3个月。这是一个柔软的红黄色肿瘤，占据整个左侧泪阜区域，未侵犯结膜。切除活检标本的组织病理学评估显示，肿瘤主要由朗格汉斯细胞组成，混有嗜酸性粒细胞和成熟淋巴细胞。免疫组织化学研究显示CD1a和S-100呈强阳性。朗格汉斯细胞组织细胞增多症是成人泪阜极为罕见的肿瘤，仅凭临床症状无法将此病变与其他无色素性病变区分开来。简单切除该病变后有4年无病期。
