Saltanov A I, Gorobets E S, Aliev U A
Anesteziol Reanimatol. 1991 Nov-Dec(6):34-7.
The study has been performed right after surgery in 20 patients of the test group (subgroups I and II) and 20 control patients. Surgery for urologic cancer has been performed in all the patients by transabdominal approach using general anesthesia based on neuroleptanesthesia (NLA). It has been shown that in patients with hypoventilation moradol, administered intravenously at a dose of 1 mg, restores adequate respiration and gas exchange. Patients with apnea upon administration of 1 mg moradol recovered respiration in hypoventilation regimen. Repeated injection of 1 mg moradol promoted the recovery of adequate respiration and gas exchange in all the patients. The patients of the test group were extubated 12.4 +/- 0.1 min on an average after the operation. Control patients, who had not been administered moradol, were extubated 20.4 +/- 0.7 min on an average after the operation. It is shown that the use of moradol in patients after NLA leads to a drastic decrease in the incidence and degree of postoperative pain syndrome and postanesthesia chill.
该研究在20例试验组患者（I组和II组）和20例对照患者术后立即进行。所有患者均采用基于神经安定麻醉（NLA）的全身麻醉经腹途径进行泌尿外科癌症手术。结果表明，对于通气不足的患者，静脉注射1mg吗多明可恢复充分的呼吸和气体交换。给予1mg吗多明后出现呼吸暂停的患者在通气不足方案下恢复了呼吸。重复注射1mg吗多明促进了所有患者充分呼吸和气体交换的恢复。试验组患者术后平均12.4±0.1分钟拔管。未给予吗多明的对照患者术后平均20.4±0.7分钟拔管。结果表明，NLA术后患者使用吗多明可显著降低术后疼痛综合征和麻醉后寒战的发生率及程度。
