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准分子原位角膜磨镶术(LASIK)中飞秒激光制瓣时的上皮下气体突破

Sub-epithelial gas breakthrough during femtosecond laser flap creation for LASIK.

作者信息

Srinivasan Sathish, Herzig Sheldon

机构信息

Herzig Eye Institute, Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Canada.

出版信息

Br J Ophthalmol. 2007 Oct;91(10):1373. doi: 10.1136/bjo.2007.129213.

Abstract

INTRODUCTION

The femtosecond laser produces photodisruption at the molecular level to generate plasma, displacing the surrounding tissue resulting in the formation of cavitation bubbles. We report a case of myopic LASIK in which a vertical gas break through the surface occurred during IntraLase femtosecond flap creation.

CASE REPORT

A 30 year-old patient underwent bilateral Wavefront guided (WaveScan, Visx, USA) LASIK. The IntraLase (FS 60) was used to create a 100 microm flap. In the right eye, during flap creation in a raster mode, subepithelial gas breakthrough was noted in two focal areas. The surgeon was able to lift the flap without creating a buttonhole. The excimer ablation procedure was performed and the flap was repositioned. On the first postoperative day uncorrected visual acuity was 20/20 in both eyes.

DISCUSSION

The incidence of flap-related complications associated with the use of motorized microkeratomes for creating corneal flap during LASIK is around 5%. For the femtosecond laser there have been previous reports of cavitation bubbles migrating to the anterior chamber resulting in poor tracking during subsequent excimer laser ablation. Vertical subepithelial gas breakthrough during femtosecond laser flap creation is rare and a PubMed search revealed no previous report of this complication. Vertical gas breakthrough occurs between the dissection plane and the subepithelial space resulting in escape of gas bubbles in to the subepithelial space. The cause is unknown but a thin flap or a focal break in the Bowman's membrane may contribute to this complication.

摘要

引言

飞秒激光在分子水平产生光致破裂以生成等离子体,使周围组织移位从而形成空化气泡。我们报告一例近视准分子原位角膜磨镶术(LASIK)病例,在使用IntraLase飞秒制瓣过程中出现垂直性气体穿透角膜表面的情况。

病例报告

一名30岁患者接受了双眼波前像差引导(美国威视WaveScan)的LASIK手术。使用IntraLase(FS 60)制作了一个100微米的角膜瓣。在右眼,以光栅模式制瓣过程中,在两个焦点区域发现上皮下气体穿透。手术医生能够提起角膜瓣而未造成纽扣孔。进行了准分子激光消融手术,然后将角膜瓣复位。术后第一天,双眼裸眼视力均为20/20。

讨论

在LASIK手术中使用电动微型角膜刀制作角膜瓣时,与瓣相关并发症的发生率约为5%。对于飞秒激光,之前有报道称空化气泡迁移至前房导致后续准分子激光消融过程中跟踪不良。飞秒激光制瓣过程中垂直性上皮下气体穿透较为罕见,PubMed检索未发现此前关于该并发症的报道。垂直性气体穿透发生在分离平面与上皮下间隙之间,导致气泡逸入上皮下间隙。原因尚不清楚,但薄角膜瓣或Bowman膜的局灶性破裂可能促成了这一并发症。

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本文引用的文献

1
Anterior chamber gas bubble formation during femtosecond laser flap creation for LASIK.
J Refract Surg. 2007 Oct;23(8):828-30. doi: 10.3928/1081-597X-20071001-14.
2
Anterior chamber gas bubbles after corneal flap creation with a femtosecond laser.
J Cataract Refract Surg. 2005 Nov;31(11):2227-9. doi: 10.1016/j.jcrs.2004.12.069.
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Incidence and management of intraoperative and early postoperative complications in 1000 consecutive laser in situ keratomileusis cases.
Ophthalmology. 1998 Oct;105(10):1839-47; discussion 1847-8. doi: 10.1016/s0161-6420(98)91026-0.

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