Graff Maud J L, Vernooij-Dassen Myrra J M, Thijssen Marjolein, Dekker Joost, Hoefnagels Willibrord H L, Olderikkert Marcel G M
Research Group of Allied Health Care, Department of Allied Health Care Disciplines, Occupational Therapy 897, University Medical Center Nijmegen, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands.
J Gerontol A Biol Sci Med Sci. 2007 Sep;62(9):1002-9. doi: 10.1093/gerona/62.9.1002.
Cure of dementia is not possible, but quality of life of patients and caregivers can be improved. Our aim is to investigate effects of community occupational therapy on dementia patients' and caregivers' quality of life, mood, and health status and caregivers' sense of control over life.
Community-dwelling patients aged 65 years or older, with mild-to-moderate dementia, and their informal caregivers (n = 135 couples of patients with their caregivers) were randomly assigned to 10 sessions of occupational therapy over 5 weeks or no intervention. Cognitive and behavioral interventions were used to train patients in the use of aids to compensate for cognitive decline and caregivers in coping behaviors and supervision. Outcomes, measured at baseline, 6 weeks, and 12 weeks, were patients' and caregivers' quality of life (Dementia Quality of Life Instrument, Dqol), patients' mood (Cornell Scale for Depression, CSD), caregivers' mood (Center for Epidemiologic Studies Depression Scale, CES-D), patients' and caregivers' health status (General Health Questionnaire, GHQ-12), and caregivers' sense of control over life (Mastery Scale).
Improvement on patients' Dqol overall (0.8; 95% confidence interval [CI], 0.6-.1, effect size 1.3) and caregivers' Dqol overall (0.7; 95% CI, 0.5-.9, effect size 1.2) was significantly better in the intervention group as compared to controls. Scores on other outcome measures also improved significantly. This improvement was still significant at 12 weeks.
Community occupational therapy should be advocated both for dementia patients and their caregivers, because it improves their mood, quality of life, and health status and caregivers' sense of control over life. Effects were still present at follow-up.
痴呆症无法治愈,但患者及其照料者的生活质量可以得到改善。我们的目的是研究社区职业治疗对痴呆症患者及其照料者的生活质量、情绪、健康状况以及照料者对生活的掌控感的影响。
年龄在65岁及以上、患有轻至中度痴呆症的社区居住患者及其非正式照料者(n = 135对患者及其照料者)被随机分配接受为期5周的10次职业治疗或不接受干预。采用认知和行为干预方法,训练患者使用辅助工具以弥补认知能力下降,并训练照料者掌握应对行为和监督技巧。在基线、6周和12周时测量的结果包括患者及其照料者的生活质量(痴呆症生活质量量表,Dqol)、患者的情绪(康奈尔抑郁量表,CSD)、照料者的情绪(流行病学研究中心抑郁量表,CES-D)、患者及其照料者的健康状况(一般健康问卷,GHQ-12)以及照料者对生活的掌控感(掌控量表)。
与对照组相比,干预组患者的总体Dqol(改善0.8;95%置信区间[CI],0.6 - 1.0,效应量1.3)和照料者的总体Dqol(改善0.7;95% CI,0.5 - 0.9,效应量1.2)有显著更好的改善。其他结果指标的得分也有显著改善。这种改善在12周时仍然显著。
应提倡对痴呆症患者及其照料者进行社区职业治疗,因为它能改善他们的情绪、生活质量和健康状况以及照料者对生活的掌控感。随访时效果仍然存在。