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白内障流行病学:25 年取得的成就及未来方向

Epidemiology of cataract: accomplishments over 25 years and future directions.

作者信息

West Sheila

机构信息

Dana Center for Preventive Ophthalmology, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

出版信息

Ophthalmic Epidemiol. 2007 Jul-Aug;14(4):173-8. doi: 10.1080/09286580701423151.

Abstract

The purpose of this review is to highlight the advances made by epidemiologic research into cataract. Considerable progress has been made in characterizing phenotypes, determining the prevalence and incidence in various population groups, and understanding risk factors for cataract. Cataract surgery research has documented functional improvements following surgery and has identified aspects of surgery delivery that could be made. Cataract is an independent marker of early mortality, providing a possible system for studying the aging process. Promising future work in cataract epidemiology is highlighted. Despite the availability of cataract surgery, cataract is still the leading cause of blindness worldwide. From a public health standpoint, research that can identify ways to delay onset or progression, or achieve the holy grail of prevention of cataract, should remain a leading priority.

摘要

本综述的目的是强调流行病学研究在白内障领域所取得的进展。在白内障表型特征描述、确定不同人群中的患病率和发病率以及了解白内障危险因素方面已取得了相当大的进展。白内障手术研究记录了手术后的功能改善情况,并确定了手术实施方面可改进之处。白内障是早期死亡的一个独立标志物,为研究衰老过程提供了一个可能的系统。文中强调了白内障流行病学未来有前景的工作。尽管有白内障手术可用,但白内障仍是全球失明的主要原因。从公共卫生角度来看,能够确定延缓发病或进展方法或实现预防白内障这一圣杯的研究仍应是首要优先事项。

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