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原发性高血压患者舒张压与认知功能障碍体征的相关性

Correlation of diastolic blood pressure and signs of cognitive dysfunction in essential hypertension.

作者信息

Goldman H, Kleinman K M, Snow M Y, Bidus D R, Korol B

机构信息

Neuropsychology Laboratory, Veterans Administration Hospital, Jefferson Barracks Division, St. Louis, Missouri 63125, USA.

出版信息

Dis Nerv Syst. 1974 Dec;35(12):571-2.

PMID:17896757
Abstract

A significant positive relationship was obtained between degree of diastolic hypertension and frequency of errors made on a psychological test sensitive to cognitive dysfunction in a sample of essential hypertensives. The significance of the relationship, (a) was obtained in spite of a small sample size and (b) persisted even after the possible confounding variables of age and IQ were statistically eliminated. These findings imply that essential hypertension may result in cognitive impairment as well as damage to other organ systems.

摘要

在原发性高血压患者样本中,舒张期高血压程度与一项对认知功能障碍敏感的心理测试中的错误频率之间存在显著正相关。这种关系的显著性,(a)尽管样本量较小仍得以获得,并且(b)即使在年龄和智商等可能的混杂变量经统计学消除后依然存在。这些发现意味着原发性高血压可能导致认知障碍以及对其他器官系统的损害。

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引用本文的文献

1
Hypertension and cognitive function.高血压与认知功能
J Clin Psychol Med Settings. 1995 Sep;2(3):233-48. doi: 10.1007/BF01990879.
2
Cognitive function and cardiovascular responsivity in subjects with a parental history of hypertension.
J Behav Med. 1993 Jun;16(3):277-94. doi: 10.1007/BF00844760.
3
Cognitive function in hypertensives treated with atenolol or propranolol.
J Gen Intern Med. 1990 Jul-Aug;5(4):310-8. doi: 10.1007/BF02600398.
4
Hypertension: cognitive and behavioral considerations.
高血压:认知与行为方面的考量
Neuropsychol Rev. 1990 Mar;1(1):31-73. doi: 10.1007/BF01108858.
5
The effects of mild diastolic hypertension on the results of tests of cognitive function in adults 22 to 59 years of age.
J Gen Intern Med. 1992 Jan-Feb;7(1):19-25. doi: 10.1007/BF02599096.
6
Behavioral medicine approaches to hypertension: an integrative analysis of theory and research.高血压的行为医学方法:理论与研究的综合分析
J Behav Med. 1979 Dec;2(4):311-63. doi: 10.1007/BF00844739.