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中国贵州务川手工汞矿冶炼工人的汞暴露与症状

Mercury exposures and symptoms in smelting workers of artisanal mercury mines in Wuchuan, Guizhou, China.

作者信息

Li Ping, Feng Xinbin, Qiu Guangle, Li Zhonggen, Fu Xuewu, Sakamoto Minishi, Liu Xiaojie, Wang Dingyong

机构信息

State Key Laboratory of Environmental Geochemistry, Institute of Geochemistry, Chinese Academy of Sciences, 46 Guanshui Road, Guiyang 550002, China.

出版信息

Environ Res. 2008 May;107(1):108-14. doi: 10.1016/j.envres.2007.08.003. Epub 2007 Sep 25.

DOI:10.1016/j.envres.2007.08.003
PMID:17897640
Abstract

Mercury exposures to smelting workers of artisanal mercury mines in Wuchuan, Guizhou, China were evaluated by urine and hair mercury survey. The mean urinary mercury (U-Hg), hair total mercury (T-Hg), and hair methyl mercury (Me-Hg) for smelting workers was 1060 microg/g creatinine (microg/g Cr), 69.3 and 2.32 microg/g, respectively. The results were significantly higher than that of control group, which is 1.30 microg/g Cr, 0.78 and 0.65 microg/g, correspondingly. The average urinary beta2-microglobulin (beta2-MG) was 248 microg/g Cr for the exposed group contrasting to 73.5 microg/g Cr for the control group and the data showed a serious adverse effect on renal system for the smelting workers. The workers were exposed to mercury vapor through inhalation, and the exposure route of Me-Hg may be through intake of polluted diet. The results indicate that age, alcohol drinking, and smoking are not crucial factors controlling the urine and hair mercury levels for the exposed and the control group. Clinical symptoms including finger and eyelid tremor, gingivitis, and typical dark-line on gums were observed in six workers. This study indicated that the smelting workers in Wuchuan were seriously exposed to mercury vapor.

摘要

通过尿液和头发汞含量检测,对中国贵州务川手工汞矿冶炼工人的汞暴露情况进行了评估。冶炼工人的尿汞(U-Hg)、头发总汞(T-Hg)和头发甲基汞(Me-Hg)平均含量分别为1060微克/克肌酐(μg/g Cr)、69.3微克/克和2.32微克/克。这些结果显著高于对照组,对照组相应的含量分别为1.30微克/克肌酐、0.78微克/克和0.65微克/克。暴露组尿β2-微球蛋白(β2-MG)平均含量为248微克/克肌酐,而对照组为73.5微克/克肌酐,数据表明冶炼工人的肾脏系统受到了严重的不良影响。工人通过吸入接触汞蒸气,甲基汞的接触途径可能是摄入受污染的饮食。结果表明,年龄、饮酒和吸烟并非控制暴露组和对照组尿液和头发汞含量的关键因素。在6名工人中观察到了包括手指和眼睑震颤、牙龈炎以及牙龈上典型黑线在内的临床症状。该研究表明,务川的冶炼工人严重暴露于汞蒸气中

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