Sims Rebecca J A, Taylor Rachel, Masud Tahir, Roe Simon, Cassidy Michael J D, Mockett Simon
Department of Renal and Transplant Medicine, Nottingham University Hospitals NHS Trust, City Hospital Campus, Hucknall Road, Nottingham, NG5 1PB, UK.
Int Urol Nephrol. 2007;39(4):1287-93. doi: 10.1007/s11255-007-9280-0. Epub 2007 Sep 26.
To undertake balance and functional mobility assessments in older maintenance haemodialysis patients before and after haemodialysis as a pilot study in order to gain initial data and to assess the feasibility and acceptability of this type of study.
Postural sway, three-metre timed "up and go" test (TGUGT), and dynamic single leg extensor power (LEP) were measured before and after a haemodialysis session.
Male and female maintenance haemodialysis patients aged over 60 years attending the Nottingham City Hospital.
Objective outcome measures were postural sway number and sway path (mm) by balance performance monitor, timed three-metre "up and go" test (s), and leg extensor power (W). Blood pressure and weight reductions were also measured. Subjective assessments of practicality and acceptability were made.
Twenty-two patients enrolled. Complete data sets were collected for 14 subjects (11 male, three female). Results were analysed using the Wilcoxon signed ranks test for nonparametric data. There was no significant difference before and after dialysis in postural sway, timed "up and go" or leg extensor power. Eight patients did not complete the study and the reasons are examined.
There was no significant single-session effect. Results suggest that haemodialysis patients may be weaker and have reduced postural stability when compared to historical data on comparable undialysed patients. The study was logistically complex and would be difficult to expand using these methods, but the issues merit further consideration.
对老年维持性血液透析患者在血液透析前后进行平衡和功能移动性评估,作为一项试点研究,以获取初步数据,并评估此类研究的可行性和可接受性。
在一次血液透析疗程前后测量姿势摆动、三米定时“起身走”测试(TGUGT)和动态单腿伸肌力量(LEP)。
诺丁汉市医院60岁以上的男性和女性维持性血液透析患者。
客观结果指标包括通过平衡性能监测仪测量的姿势摆动次数和摆动路径(毫米)、三米定时“起身走”测试(秒)以及腿部伸肌力量(瓦特)。还测量了血压和体重减轻情况。进行了实用性和可接受性的主观评估。
22名患者入组。为14名受试者(11名男性,3名女性)收集了完整数据集。使用威尔科克森符号秩检验对非参数数据进行分析。透析前后在姿势摆动、定时“起身走”或腿部伸肌力量方面无显著差异。8名患者未完成研究,并对原因进行了检查。
单次透析没有显著效果。结果表明,与未透析的可比患者的历史数据相比,血液透析患者可能更虚弱且姿势稳定性降低。该研究在后勤方面很复杂,使用这些方法难以扩大规模,但这些问题值得进一步考虑。