Moist Louise M, Chang Sean H, Polkinghorne Kevan R, McDonald Stephen P
Division of Nephrology, London Health Sciences Center, University of Western Ontario, London, Ontario, Canada.
Am J Kidney Dis. 2007 Oct;50(4):612-21. doi: 10.1053/j.ajkd.2007.07.016.
Australia historically has been recognized for its high fistula use.
Observational study using registry data.
SETTING & PARTICIPANTS: Adult patients registered in the Australia and New Zealand Dialysis and Transplant Association Registry on hemodialysis in Australia.
Cohort year.
OUTCOMES & MEASUREMENT: Hemodialysis access trends were examined from 2000 to 2005 for incident patients (within 60 days of hemodialysis therapy start), patients on hemodialysis therapy for 6 to 8 months, and prevalent hemodialysis patients. Multivariate analyses were performed to examine the relationship between access type and cohort year for each group, with adjustment for age, sex, race, body mass index, late referral, smoking status, cause of end-stage renal disease, comorbidities, and dialysis vintage.
During 2000 to 2005, catheter use increased from 39% to 53% in incident patients, 10% to 22% in the 6- to 8-month groups, and 6% to 13% in prevalent patients. Fistula use decreased from 56% to 43% in incident patients and 78% to 67% in the 6- to 8-month group and remained at 73% to 75% in prevalent patients. Graft use decreased in all groups. Adjustment for factors associated with access type did not significantly change these results.
The registry collects only the access in use at the end of the survey period; thus, it was not possible to determine whether another access had failed or was present, but not in use. The small number of incident numbers prevented separate analysis of arteriovenous fistulas and arteriovenous grafts.
Incident use of fistulas and grafts decreased, with an unexpected increase in both incident and prevalent catheters between 2000 and 2005. Adjustment for factors associated with access type did not significantly alter the trends. Changes in unidentified practice patterns, attitudes, or preferences are contributing to these trends. Ongoing evaluation of data and investigation into processes of care are required to increase functioning fistulas, together with reevaluation of the role of grafts in patients without a fistula.
澳大利亚历来以其较高的瘘管使用率而闻名。
使用登记数据的观察性研究。
在澳大利亚和新西兰透析与移植协会登记处登记的澳大利亚接受血液透析的成年患者。
队列年份。
对2000年至2005年期间的新发病例患者(血液透析治疗开始后60天内)、接受血液透析治疗6至8个月的患者以及长期血液透析患者的血液透析通路趋势进行了研究。对每组患者进行多变量分析,以检查通路类型与队列年份之间的关系,并对年龄、性别、种族、体重指数、延迟转诊、吸烟状况、终末期肾病病因、合并症和透析时间进行了调整。
在2000年至2005年期间,新发病例患者的导管使用率从39%增至53%,6至8个月组从10%增至22%,长期患者从6%增至13%。新发病例患者的瘘管使用率从56%降至43%,6至8个月组从78%降至67%,长期患者则保持在73%至75%。所有组的移植物使用率均下降。对与通路类型相关的因素进行调整后,这些结果没有显著变化。
该登记处仅收集调查期结束时正在使用的通路信息;因此,无法确定是否有其他通路失败或存在但未使用。新发病例数量较少,无法对动静脉瘘和动静脉移植物进行单独分析。
2000年至2005年期间,瘘管和移植物的新发病例使用率下降,新发病例和长期患者的导管使用率意外增加。对与通路类型相关的因素进行调整并没有显著改变这些趋势。未明确的实践模式、态度或偏好的变化导致了这些趋势。需要持续评估数据并调查护理过程,以增加功能性瘘管的数量,同时重新评估移植物在没有瘘管的患者中的作用。