Rodríguez Fernández A M, Martí Peña M, González Nuñez M A, Aparicio Pérez M, Avila García J
Servicio de Anatomía Patológica, Hospital General del Insalud, Cáceres.
Acta Otorrinolaringol Esp. 1991 Nov-Dec;42(6):461-4.
The clinical and morphological features of two patients with solitary extramedullary plasmacytomas of paranasal sinus and nasal cavity are presented. Patients only developed local symptomatology without features of multiple myeloma. They were treated with surgical excision and local radiotherapy. This is the treatment of choice recommended for these localized tumors. Microscopically, one tumor contained a well-differentiated plasma cell population, and the other was made up immature cells. Cytoplasmic staining for IgG was showed in both tumors for immunoperoxidase studies. However, no serum monoclone was detected at the time of diagnosis nor later. Currently, they are alive without evidence of disease 20 and 16 months, respectively, after treatment.
本文介绍了两名患有鼻窦和鼻腔孤立性髓外浆细胞瘤患者的临床和形态学特征。患者仅出现局部症状，无多发性骨髓瘤的特征。他们接受了手术切除和局部放疗。这是针对这些局限性肿瘤推荐的首选治疗方法。显微镜下，一个肿瘤含有分化良好的浆细胞群，另一个由未成熟细胞组成。免疫过氧化物酶研究显示，两个肿瘤的细胞质均有IgG染色。然而，诊断时及之后均未检测到血清单克隆。目前，他们在治疗后分别存活了20个月和16个月，无疾病证据。
