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1983 - 1985年肯尼亚不同地区母乳中的有机氯农药

Organochlorine pesticides in human milk from different areas of Kenya 1983-1985.

作者信息

Kanja L, Skåre J U, Nafstad I, Maitai C K, Løkken P

出版信息

J Toxicol Environ Health. 1986;19(4):449-64. doi: 10.1080/15287398609530944.

Abstract

Residue levels of the chlorinated hydrocarbons p,p'-DDT (2,2-bis(p-chlorophenyl)-1,1,1-trichloroethane), p,p'-DDE (2,2-bis(p-chlorophenyl)-1,1-dichloroethane), hexachlorobenzene (HCB), alpha-, beta-, and gamma-hexachlorocyclohexane (HCH), aldrin, dieldrin, and polychlorinated biphenyls (PCBs) were determined in human milk of Kenyan mothers living in different areas of Kenya. The main organochlorine contaminants found in all the milk samples analyzed were p,p'-DDT and p,p'-DDE. Great regional differences were found, and mean levels of sum DDT and DDT/DDE ratio ranged from 1.1 to 18.7 mg/kg milk fat and from 0.7 to 5.7, respectively. In general, relatively low residue levels of HCB, alpha-HCH, beta-HCH, aldrin, and dieldrin were detected in 59, 37, 27, 37, and 19%, respectively, of all the milk samples analyzed. Quantifiable residue levels of PCBs and alpha-HCH were not found. The results were examined in relation to differences in living conditions with regard to agricultural activities, dietary habits, and reported use of pesticides in the various sampling areas.

摘要

对生活在肯尼亚不同地区的肯尼亚母亲的母乳进行了检测,以测定其中的氯代烃类物质,包括对,对'-滴滴涕(2,2-双(对氯苯基)-1,1,1-三氯乙烷)、对,对'-滴滴伊(2,2-双(对氯苯基)-1,1-二氯乙烷)、六氯苯(HCB)、α-、β-和γ-六氯环己烷(HCH)、艾氏剂、狄氏剂以及多氯联苯(PCBs)的残留水平。在所分析的所有母乳样本中,主要的有机氯污染物为对,对'-滴滴涕和对,对'-滴滴伊。研究发现了显著的地区差异,总滴滴涕的平均水平和滴滴涕/滴滴伊的比例分别在1.1至18.7毫克/千克乳脂之间以及0.7至5.7之间。总体而言,在所分析的所有母乳样本中,分别有59%、37%、27%、37%和19%的样本检测到六氯苯、α-六氯环己烷、β-六氯环己烷、艾氏剂和狄氏剂的残留水平相对较低。未发现多氯联苯和α-六氯环己烷的可量化残留水平。结合不同采样地区在农业活动、饮食习惯以及报告的农药使用情况等生活条件方面的差异,对结果进行了分析。

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