Ham Maggie, Horton Kelli, Kaunitz Jonathan
School of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA 90073, USA.
Nutr Clin Pract. 2007 Oct;22(5):553-7. doi: 10.1177/0115426507022005553.
Enterocutaneous fistulae are a common postoperative entity, causing serious complications such as sepsis, malnutrition, and electrolyte and fluid abnormalities. Because sepsis coupled with malnutrition is the leading cause of death in these patients, it is especially important to provide nutrition support. Although parenteral nutrition (PN) is widely used in these patients, it is not without risks, because PN is known to cause liver dysfunction, among other problems. We report a case in which a male patient with an enterocutaneous fistula, having experienced increased liver enzymes receiving PN, began receiving enteral nutrition (EN) via a feeding tube placed in the fistula. Known as fistuloclysis, this method provided adequate nutrition and improved his serum albumin and prealbumin levels, body weight, and liver function tests. Upon stabilization of his nutrition status, he was able to undergo successful surgical repair of the enterocutaneous fistula. According to our experience and that of others, we recommend that patients with high-output enterocutaneous fistulae be considered for EN via fistuloclysis after nutrition stabilization with PN; then the fistulae can be surgically repaired if not spontaneously healed. Use of EN via fistuloclysis, if used appropriately, avoids the complications of long-term PN and may promote faster fistula healing.
肠皮肤瘘是一种常见的术后病症,会引发严重并发症,如败血症、营养不良以及电解质和液体异常。由于败血症与营养不良是这些患者死亡的主要原因,提供营养支持尤为重要。尽管肠外营养(PN)在这些患者中被广泛使用,但它并非没有风险,因为已知PN会导致肝功能障碍等问题。我们报告了一例患有肠皮肤瘘的男性患者,在接受PN期间出现肝酶升高,随后通过置于瘘管的饲管开始接受肠内营养(EN)。这种方法被称为瘘管灌洗,它提供了充足的营养,改善了患者的血清白蛋白和前白蛋白水平、体重以及肝功能检查结果。在其营养状况稳定后,他能够成功接受肠皮肤瘘的手术修复。根据我们以及其他人的经验,我们建议在通过PN使营养状况稳定后,对于高流量肠皮肤瘘患者考虑通过瘘管灌洗进行EN;如果瘘管未自行愈合,则可进行手术修复。如果适当使用,通过瘘管灌洗进行EN可避免长期PN的并发症,并可能促进瘘管更快愈合。