Meyer Thorsten, Cooper James, Raspe Heiner
Institute of Social Medicine, Medical University Schleswig-Holstein, Campus Luebeck, Luebeck, Germany.
Spine (Phila Pa 1976). 2007 Oct 1;32(21):2380-6. doi: 10.1097/BRS.0b013e3181557955.
Analytic cross-sectional and cohort study.
This study examines the prevalence and associations of low back pain (LBP) and depressive symptoms in a large population of elderly (65+), community-dwelling subjects.
In adults, depression has been identified as predictive for LBP, while depression has also been found to be a possible consequence of LBP.
Data of the Health Outcomes Survey that include a baseline (N = 91,347) and a follow-up survey (N = 55,690) after 2 years were analyzed cross-sectionally and prospectively. Degree of depressive symptoms and disabling LBP were described at both time points, as well as their interrelationships. An ordinal logistic regression analysis was performed to model the effects of different sociodemographic, clinical, and functional variables on LBP and depressive symptoms after 2 years.
Depressive symptoms were found in about 20% of the sample. Baseline depression symptoms increased the odds of disabling LBP after 2 years independently of sociodemographic characteristics, medical, and functional status. Disabling LBP at baseline increased the odds of depressive symptoms after 2 years to a similar degree.
Among community-dwelling elderly persons, depressive symptoms and disabling LBP are widespread. Depressive symptoms predict disabling LBP and vice versa. The set of predictors and their extent of contribution to the prognosis are strikingly similar. Research is warranted to identify possible common pathogenic mechanisms or mediating factors.
分析性横断面研究和队列研究。
本研究调查了大量65岁及以上社区居住老年人中腰痛(LBP)和抑郁症状的患病率及其相关性。
在成年人中,抑郁已被确定为腰痛的预测因素,同时抑郁也被发现可能是腰痛的后果。
对健康结果调查的数据进行横断面和前瞻性分析,该数据包括基线调查(N = 91347)和2年后的随访调查(N = 55690)。在两个时间点描述抑郁症状的程度和致残性腰痛情况,以及它们之间的相互关系。进行有序逻辑回归分析,以模拟不同社会人口统计学、临床和功能变量对2年后腰痛和抑郁症状的影响。
约20%的样本存在抑郁症状。基线时的抑郁症状独立于社会人口统计学特征、医疗和功能状态,增加了2年后致残性腰痛的几率。基线时的致残性腰痛在相似程度上增加了2年后出现抑郁症状的几率。
在社区居住的老年人中,抑郁症状和致残性腰痛很普遍。抑郁症状可预测致残性腰痛,反之亦然。预测因素及其对预后的贡献程度非常相似。有必要开展研究以确定可能的共同致病机制或中介因素。