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Lowering serum uric acid levels: what is the optimal target for improving clinical outcomes in gout?

作者信息

Perez-Ruiz Fernando, Lioté Frédéric

机构信息

Hospital de Cruces, Baracaldo, Pais Vasco, Spain.

出版信息

Arthritis Rheum. 2007 Oct 15;57(7):1324-8. doi: 10.1002/art.23007.

DOI:10.1002/art.23007
PMID:17907217
Abstract
摘要

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Lowering serum uric acid levels: what is the optimal target for improving clinical outcomes in gout?降低血清尿酸水平:改善痛风临床结局的最佳目标是什么?
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Disease-specific noncompliance with drug treatment as a cause of persistent hyperuricemia and gout in anorexia nervosa.特定疾病导致的药物治疗不依从作为神经性厌食症中持续性高尿酸血症和痛风的一个病因
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Treatment with allopurinol decreases the number of acute gout attacks despite persistently elevated serum uric acid levels.尽管血清尿酸水平持续升高,但使用别嘌醇治疗可减少急性痛风发作的次数。
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Clinical efficacy and safety of successful longterm urate lowering with febuxostat or allopurinol in subjects with gout.非布司他或别嘌醇成功长期降低痛风患者尿酸水平的临床疗效与安全性
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Impact of noncompliance with urate-lowering drug on serum urate and gout-related healthcare costs: administrative claims analysis.降尿酸药物治疗依从性不佳对血清尿酸及痛风相关医疗费用的影响:行政索赔分析
Curr Med Res Opin. 2009 Jul;25(7):1711-9. doi: 10.1185/03007990903017966.

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