Liu Ling-guang, Zhang Hong-xing
Department of Acu-moxibustion, Wuhan Hospital of Integrated Chinese & Western Medicine, China.
Zhen Ci Yan Jiu. 2007 Aug;32(4):277-80.
Recent studies indicate that nerve stem cells (NSC) plays a role in the pathophysiological process of cerebral ischemia which could activate the proliferation and differentiation of endogenous NSC. Scalp-acupuncture therapy has a good effect in the treatment of ischemic stroke, hence, we presume that there exists a possibility that endogenous NSC may contribute to the effect of scalp-acupuncture in promoting the repair and remodeling of the injured ischemic cerebral tissue. Thus, in the present paper, the authors review development of researches on NSC both at home and abroad from clinical therapeutic effect and experimental research, and discuss the possible role or significance of NSC in the treatment of ischemic cerebral stroke with scalp-acupuncture therapy, so as to reveal the regulative mechanism of scalp-acupuncture on endogenous NSC and to make a better use of scalp-acupuncture therapy in accelerating the proliferation and differentiation of NSO, and to lay a solid theoretical foundation for future clinical application.
近期研究表明,神经干细胞(NSC)在脑缺血的病理生理过程中发挥作用,这可能会激活内源性神经干细胞的增殖和分化。头针疗法在缺血性中风的治疗中具有良好效果,因此,我们推测内源性神经干细胞有可能对头针促进受损缺血性脑组织修复和重塑的效果产生作用。因此,在本文中,作者从临床治疗效果和实验研究两方面综述了国内外神经干细胞的研究进展,并探讨神经干细胞在头针疗法治疗缺血性脑中风中的可能作用或意义,以揭示头针对内源性神经干细胞的调节机制,更好地利用头针疗法促进神经干细胞的增殖和分化,为未来的临床应用奠定坚实的理论基础。