[氟喹诺酮类药物引起的肌腱疾病]

[Fluoroquinolone-induced tendon diseases].

作者信息

Medrano San Ildefonso M, Mauri Llerda J A, Bruscas Izu C

机构信息

Sección de Reumatología, Hospital Universitario Miguel Servet, Zaragoza.

出版信息

An Med Interna. 2007 May;24(5):227-30. doi: 10.4321/s0212-71992007000500005.

DOI:10.4321/s0212-71992007000500005

PMID:17907887

Abstract

Tendinitis and tendon ruptures induced by fluoroquinolones, while uncommon, have been documented in the literature since 1983. We report five cases of tendinitis induced by fluoroquinolones, three caused by levofloxacin and two by ciprofloxacin. We revise actual knowledge of this association and we insist on how important is an early detection to prevent tendon rupture.

摘要

自1983年以来，文献中已记载氟喹诺酮类药物引起的肌腱炎和肌腱断裂，虽然并不常见。我们报告了5例氟喹诺酮类药物引起的肌腱炎病例，其中3例由左氧氟沙星引起，2例由环丙沙星引起。我们回顾了关于这种关联的现有知识，并强调早期检测对于预防肌腱断裂的重要性。