Tam P K, Ho Carmen T K
Department of Medicine, Tung Wah Hospital, 12 Po Yan Street, Sheung Wan, Hong Kong.
Hong Kong Med J. 2014 Dec;20(6):545-7. doi: 10.12809/hkmj134105.
We report a case of Achilles tendinitis after intake of ciprofloxacin for treatment of respiratory tract infection. Fluoroquinolone-induced tendinopathy is an uncommon but increasingly recognised adverse effect of this antibiotic class. Most of the cases occur in the Achilles tendon and may lead to tendon rupture. Possible predisposing risk factors include use of steroid, patients with renal impairment or renal transplant, old age, and being an athlete. The drug should be stopped once this condition is suspected. Symptomatic treatment should be given and orthopaedic referral is desirable if tendon rupture occurs.
我们报告了一例在服用环丙沙星治疗呼吸道感染后发生跟腱炎的病例。氟喹诺酮类药物引起的肌腱病是这类抗生素一种不常见但日益被认识到的不良反应。大多数病例发生在跟腱，可能导致肌腱断裂。可能的易感风险因素包括使用类固醇、肾功能损害或肾移植患者、老年以及运动员。一旦怀疑出现这种情况，应停用该药物。应给予对症治疗，如果发生肌腱断裂，最好转诊至骨科。
