Zhou Sitong, Yang Yemei, Liu Kangxing, Huang Shiyun, Hu Yongxuan, Zhou Xianyi
Department of Dermatology and Venerology, The 3rd Affiliated Hospital of Southern Medical University, 183 West Zhongshan Rd, Guangzhou, 510630, China.
Department of Dermatology, Shenzhen Hospital of Southern Medical University, Shenzhen, 518100, Guangdong, China.
Mycopathologia. 2017 Jun;182(5-6):577-581. doi: 10.1007/s11046-017-0109-9. Epub 2017 Jan 12.
Majocchi's granuloma is an intracutaneous or subcutaneous granulomatous inflammation caused by invasion of dermatophytic fungus, especially Trichophyton rubrum. This type of lesion is misdiagnosed frequently without proper auxiliary examination. Here, we report a case of widespread Majocchi's granuloma caused by T. rubrum in a 35-year-old woman with systemic lupus erythematosus for 9 years. The patient was initially misdiagnosed as SLE-associated skin lesions, which delayed her treatment and resulted in severe multiple disseminated lesions. After confirmed as Majocchi's granuloma, the patient was cured after 11-month treatment with terbinafine.
Majocchi 肉芽肿是一种由皮肤癣菌，尤其是红色毛癣菌侵入引起的皮内或皮下肉芽肿性炎症。这类病变若没有合适的辅助检查，常被误诊。在此，我们报告一例由红色毛癣菌引起的广泛播散性 Majocchi 肉芽肿病例，患者为一名 35 岁女性，患有系统性红斑狼疮 9 年。该患者最初被误诊为系统性红斑狼疮相关的皮肤病变，这延误了她的治疗，导致出现严重的多发播散性病变。确诊为 Majocchi 肉芽肿后，患者经特比萘芬治疗 11 个月后治愈。
