Li Xuesheng, Wang Jing, Li Hongbo, Zhang Ming
Department of Prosthodontics, Hainan Stomatological Hospital, Haikou, Hainan 570105, P.R. China.
Department of Stomatology, Hainan Branch of Chinese People's Liberation Army General Hospital, Sanya, Hainan 572013, P.R. China.
Mol Clin Oncol. 2019 Mar;10(3):352-356. doi: 10.3892/mco.2018.1793. Epub 2018 Dec 18.
Kimura's disease (KD) is a rare condition, with only a few cases reported to date, mainly in Asian patients. We herein present the case of a 48-year-old man with KD who presented with recurrent masses in the right parotid gland and neck region over a 15-year period. The masses were not accompanied by pain, or significant functional or neurosensory dysfunction. The results of the laboratory tests revealed an increased eosinophil count and markedly elevated serum IgE levels. On magnetic resonance imaging examination, a widespread abnormal signal was detected in the area of the lesions; the contrast-enhanced scan revealed inhomogeneous enhancement, with partial involvement of the sternocleidomastoid muscle and the parotid gland. The patient underwent surgical resection of the right parotid and neck masses, and the postoperative pathological examination revealed eosinophilic hyperplastic lymphogranuloma, also referred to as KD. This presented case and review of the relevant literature aim to improve our understanding of KD in order to increase the accuracy of diagnosis, reduce the misdiagnosis rate and ensure proper treatment of this rare disease.
木村病（KD）是一种罕见疾病，迄今为止仅有少数病例报道，主要见于亚洲患者。我们在此报告一例48岁患有木村病的男性患者，该患者在15年期间右侧腮腺和颈部反复出现肿块。这些肿块不伴有疼痛，也无明显的功能或神经感觉功能障碍。实验室检查结果显示嗜酸性粒细胞计数增加，血清IgE水平显著升高。磁共振成像检查发现病变区域有广泛的异常信号；增强扫描显示不均匀强化，胸锁乳突肌和腮腺部分受累。患者接受了右侧腮腺和颈部肿块的手术切除，术后病理检查显示为嗜酸性增生性淋巴肉芽肿，也称为木村病。本病例报告及相关文献复习旨在提高我们对木村病的认识，以提高诊断准确性，降低误诊率，并确保对这种罕见疾病的正确治疗。
