Boyd A S, Neldner K H
Department of Dermatology, Texas Tech University Health Sciences Center, Lubbock 79430.
J Am Acad Dermatol. 1991 Oct;25(4):593-619. doi: 10.1016/0190-9622(91)70241-s.
Lichen planus, a papulosquamous disease, in its classical presentation is characterized by pruritic violaceous papules most commonly on the extremities of middle-aged adults. It may or may not be accompanied by oral and genital mucous membrane involvement. Its course is generally self-limited for a period of several months to years, but it may last indefinitely. There are many clinical variants described, ranging from lichenoid drug eruptions to association with other diseases such as diabetes mellitus, autoimmune disease, and the graft-versus-host reaction. The relationship of these, if any, to classical lichen planus is questionable. Multiple therapeutic options exist including corticosteroids, retinoids, griseofulvin, PUVA, and cyclosporine.
扁平苔藓是一种丘疹鳞屑性疾病,其典型表现为瘙痒性紫红色丘疹,最常见于中年成年人的四肢。它可能伴有或不伴有口腔和生殖器黏膜受累。其病程通常在数月至数年的时间内自我限制,但也可能无限期持续。有许多临床变体被描述,从苔藓样药物疹到与其他疾病如糖尿病、自身免疫性疾病和移植物抗宿主反应的关联。这些变体与经典扁平苔藓之间的关系(如果有的话)尚存在疑问。有多种治疗选择,包括皮质类固醇、维甲酸、灰黄霉素、补骨脂素紫外线A光化学疗法(PUVA)和环孢素。