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[脊髓脊膜膨出患者的泌尿系统问题。诊断研究与管理]

[Urological problems in patients with meningomyelocele. Diagnostic studies and management].

作者信息

Stein R, Schröder A, Beetz R, Ermert A, Filipas D, Fisch M, Goepel M, Körner I, Schönberger B, Sparwasser C, Stöhrer M, Thüroff J W

机构信息

Urologische Klinik und Poliklinik, Klinikum der Johannes Gutenberg Universität, Langenbeck-Strasse 1, Mainz, Germany.

出版信息

Urologe A. 2007 Dec;46(12):1620-42. doi: 10.1007/s00120-007-1522-3.

Abstract

Since the 1980s the management of children and adolescents with meningomyelocele has undergone major changes. The introduction of pharmacotherapy with antimuscarinic agents, clean intermittent catheterization (CIC) and antibacterial prophylaxis has revolutionized the management of children with neurogenic bladder. The co-operation between neonatologists, neurosurgeons, paediatric neurologists, paediatricians, paediatric urologists, paediatric nephrologists, paediatric orthopaedists and paediatric surgeons is necessary to achieve an optimized therapy in each individual patient. In this interdisciplinary consensus paper we provide definitions and classifications as well as a timetable for the appropriate investigations. The conservative and surgical options are explained in detail. A short review is given concerning orthopaedic management, incidence of latex allergy, options for bowel management, diagnosis and treatment of urinary tract infections, problems with sexuality and fertility as well as the long-term compliance of these patients and their relatives.

摘要

自20世纪80年代以来,患有脊髓脊膜膨出的儿童和青少年的管理方式发生了重大变化。抗毒蕈碱药物的药物治疗、清洁间歇性导尿(CIC)和抗菌预防的引入彻底改变了神经源性膀胱患儿的管理方式。新生儿科医生、神经外科医生、儿科神经科医生、儿科医生、儿科泌尿科医生、儿科肾病科医生、儿科骨科医生和儿科外科医生之间的合作对于为每个患者实现优化治疗是必要的。在这份跨学科共识文件中,我们提供了定义、分类以及进行适当检查的时间表。详细解释了保守和手术选择。对骨科管理、乳胶过敏的发生率、肠道管理的选择、尿路感染的诊断和治疗、性和生育问题以及这些患者及其亲属的长期依从性进行了简要综述。

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