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[脊髓脊膜膨出患者的神经源性膀胱功能障碍:S2k诊断与治疗指南]

[Neurogenic bladder function disorders in patients with meningomyelocele: S2k guidelines on diagnostics and therapy].

作者信息

Stein R, Assion C, Beetz R, Bürst M, Cremer R, Ermert A, Goepel M, Kuwertz-Bröking E, Ludwikowski B, Michael T, Pannek J, Peters H, Rohrmann D, Rübben I, Schröder A, Trollmann R, Thüroff J W, Wagner W

机构信息

Arbeitskreis Kinder- und Jugendurologie der deutschen Gesellschaft für Urologie, Universitätsmedizin Mainz, Johannes Gutenberg-Universität Mainz, Langenbeck Straße 1, 55131, Mainz, Deutschland,

出版信息

Urologe A. 2015 Feb;54(2):239-53. doi: 10.1007/s00120-013-3403-2.

DOI:10.1007/s00120-013-3403-2
PMID:25690576
Abstract

The treatment of children and adolescents with meningomyelocele has experienced a clear change in the last 30 years. The establishment of pharmacotherapy, clean intermittent catheterization (CIC) and infection prophylaxis have improved the prognosis for patients and have led to new therapeutic strategies. The interdisciplinary cooperation between neonatologists, neurosurgeons, pediatric neurologists, pediatric urologists, pediatric nephrologists, pediatric orthopedists and pediatric surgeons leads to optimization of individualized therapy. These guidelines present definitions and classifications, investigations and timing which are described in detail. The conservative and operative therapy options for neurogenic bladder function disorders are described and discussed with reference to the current literature. The brief overview provides in each case assistance for the treating physician in the care of this patient group and facilitates the interdisciplinary cooperation.

摘要

在过去30年里,患有脊髓脊膜膨出的儿童和青少年的治疗方法发生了明显变化。药物治疗、清洁间歇性导尿(CIC)和感染预防措施的建立改善了患者的预后,并催生了新的治疗策略。新生儿科医生、神经外科医生、儿科神经科医生、儿科泌尿科医生、儿科肾病科医生、儿科骨科医生和儿科外科医生之间的跨学科合作实现了个体化治疗的优化。这些指南详细介绍了定义、分类、检查和时机。文中参照当前文献描述并讨论了神经源性膀胱功能障碍的保守和手术治疗方案。这篇简要概述为治疗医生护理该患者群体提供了各方面的帮助,并促进了跨学科合作。

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[Neurogenic bladder function disorders in patients with meningomyelocele: S2k guidelines on diagnostics and therapy].[脊髓脊膜膨出患者的神经源性膀胱功能障碍:S2k诊断与治疗指南]
Urologe A. 2015 Feb;54(2):239-53. doi: 10.1007/s00120-013-3403-2.
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[Urological problems in patients with meningomyelocele. Diagnostic studies and management].[脊髓脊膜膨出患者的泌尿系统问题。诊断研究与管理]
Urologe A. 2007 Dec;46(12):1620-42. doi: 10.1007/s00120-007-1522-3.
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Management of neurogenic bladder patients in The Netherlands: do urologists follow guidelines?荷兰神经源性膀胱患者的管理:泌尿科医生是否遵循指南?
Neurourol Urodyn. 2008;27(8):758-62. doi: 10.1002/nau.20582.
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[Neuro-urological diagnosis and therapy of lower urinary tract dysfunction in patients with spinal cord injury : S2k Guideline of the German-Speaking Medical Society of Paraplegia (DMGP), AWMF register no. 179/001].[脊髓损伤患者下尿路功能障碍的神经泌尿学诊断与治疗:德语区截瘫医学协会(DMGP)S2k指南,德国医学质量与效率研究所登记号179/001]
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Clean intermittent catheterization for meningomyelocele.脊髓脊膜膨出的清洁间歇性导尿术
Wis Med J. 1975 Oct;74(10):S117-8.
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[Concept, monitoring program and results of ambulatory care of children with meningomyelocele (spina bifida)].
Monatsschr Kinderheilkd. 1990 Aug;138(8):457-60.
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[Neurogenic bladder caused by meningomyelocele in childhood: urodynamic pattern and treatment regimens].[儿童脊髓脊膜膨出所致神经源性膀胱:尿动力学模式及治疗方案]
Arch Esp Urol. 1990 May;43(4):371-4.
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Initial urological evaluation and management of children with neurogenic bladder due to myelomeningocele.脊髓脊膜膨出所致神经源性膀胱患儿的初始泌尿外科评估与管理
J Pediatr Urol. 2017 Jun;13(3):271.e1-271.e5. doi: 10.1016/j.jpurol.2016.12.024. Epub 2017 Jan 30.
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[Results of intermittent catheterization in neurogenic bladder in children and adolescents. 165 cases from 1976 to 1986].[儿童及青少年神经源性膀胱间歇性导尿的结果。1976年至1986年的165例病例]
Chir Pediatr. 1987;28(6):269-75.
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The results of clean intermittent catheterization on the abnormal upper urinary tracts of children with myelomeningocele.
Ohio State Med J. 1981 Jun;77(6):377-9.

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Importance of urodynamic evaluation of bladder function after secondary untethering in spina bifida patients: single center experience of 30 years.二次松解后路脊膜膨出患者膀胱功能尿动力学评估的重要性:30 年单中心经验
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本文引用的文献

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EAU guidelines on assessment and nonsurgical management of urinary incontinence.EAU 指南:尿失禁的评估和非手术治疗。
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Detecting reduced renal function in children: comparison of GFR-models and serum markers.检测儿童肾功能减退:肾小球滤过率模型和血清标志物的比较。
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新型大鼠骶骨脊神经损伤模型的功能、形态和分子特征-手术入路、病理过程及临床相关性。
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Pharmacotherapy for Pediatric Neurogenic Bladder.小儿神经源性膀胱的药物治疗
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Clinical usefulness of the transobturator sub-urethral tape in the treatment of stress urinary incontinence in female patients with spinal cord lesion.经闭孔尿道下吊带术治疗脊髓损伤女性患者压力性尿失禁的临床效用
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Prerequisite for successful surgical outcome in urothelium lined seromuscular colocystoplasty.在尿路上皮衬里的浆膜肌层膀胱扩大术中获得成功手术结果的前提条件。
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Febrile urinary tract infections in young children: recommendations for the diagnosis, treatment and follow-up.小儿发热性尿路感染:诊断、治疗和随访建议。
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The use of systemic and topical fluoroquinolones.氟喹诺酮类药物的全身和局部应用。
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