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清洁间歇性导尿在儿童神经源性膀胱管理中的应用

Clean intermittent catheterization in the management of the neurogenic bladder in children.

作者信息

Cass A S, Luxenberg M, Gleich P, Johnson C F, Hagen S

出版信息

J Urol. 1984 Sep;132(3):526-8. doi: 10.1016/s0022-5347(17)49720-5.

Abstract

Clean intermittent catheterization has been successful in the management of urinary incontinence and upper tract changes associated with a neurogenic bladder. The results of clean intermittent catheterization controlling urinary incontinence, ureteral reflux, upper tract dilatation and urinary infection in 84 children with a neurogenic bladder were evaluated for up to 3 years of followup. Of the children 41 (49 per cent) were totally incontinent and 14 (17 per cent) were slightly damp. Preexisting ureteral reflux deteriorated in 25 per cent of the patients, ceased in 35 per cent and was unchanged in 40 per cent, while pre-existing upper tract dilatation improved in 12.5 per cent and was unchanged in 87.5 per cent. On clean intermittent catheterization and antibacterial medication 90 per cent of the children had sterile urine and 7.5 per cent had 10(5) or more colonies per ml. Complications occurred on 54 occasions but were minor in nature and were corrected easily. Half of the parents, schools and children found clean intermittent catheterization very acceptable or acceptable but a quarter of the parents and patients found it unacceptable or slightly unacceptable, or were undecided. Initial management of urinary complications associated with neurogenic bladder in children has changed to the clean intermittent catheterization program, with greatly improved results compared to Credé's expression of the bladder, an indwelling urethral catheter or urinary diversion. However, the clean intermittent catheterization regimen was not effective completely, not without complications and not accepted completely by parents, schools and children.

摘要

清洁间歇性导尿在治疗与神经源性膀胱相关的尿失禁及上尿路改变方面已取得成功。对84例神经源性膀胱患儿进行清洁间歇性导尿,观察其控制尿失禁、输尿管反流、上尿路扩张及泌尿系统感染的效果,随访时间长达3年。这些患儿中,41例(49%)完全尿失禁,14例(17%)轻度尿湿。25%的患者原有输尿管反流病情恶化,35%的患者反流停止,40%的患者反流情况未变;而原有上尿路扩张的患者中,12.5%病情改善,87.5%病情未变。采用清洁间歇性导尿及抗菌药物治疗后,90%的患儿尿液无菌,7.5%的患儿每毫升尿液中有10⁵个或更多菌落。共发生54次并发症,但均较轻微,易于纠正。一半的家长、学校和患儿认为清洁间歇性导尿非常可接受或可接受,但四分之一的家长和患者认为不可接受或略不可接受,或持不确定态度。儿童神经源性膀胱相关泌尿系统并发症的初始治疗已转变为清洁间歇性导尿方案,与膀胱按压法、留置尿道导管或尿流改道术相比,效果有了显著改善。然而,清洁间歇性导尿方案并非完全有效,并非没有并发症,也未完全被家长、学校和患儿接受。

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