Berman Claudia G
Radiology Service, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL 33612, USA.
Cancer Control. 2007 Oct;14(4):338-49. doi: 10.1177/107327480701400404.
Imaging the breast is a vital component not only for breast cancer screening, but also for diagnosis, evaluation, treatment, and follow-up of patients with breast cancer.
The author reviews recent advances and also provides her personal experience in describing the status of digital mammography, computer-aided detection, dedicated magnetic resonance imaging (MRI), and positron-emission mammography for evaluating the breast.
Full-field digital mammography is superior to standard mammography in women under 50 years of age and in those with dense breasts. Computer-aided detection assists inexperienced mammographers and enhances detection of microcalcifications in dense breasts. Breast MRI is useful in preoperative evaluation, clarification of indeterminate mammograms, and follow-up of BRCA mutation carriers. The specificity of MRI remains problematic, however. Positron-emission mammography promises enhanced detection of ductal carcinoma in situ (DCIS), even when not associated with microcalcifications, and should aid surgical planning.
These four significant advances in breast imaging have all improved the sensitivity of detecting breast abnormalities. Cost issues, however, may limit the widespread application of these advances.
乳腺成像不仅是乳腺癌筛查的重要组成部分,也是乳腺癌患者诊断、评估、治疗及随访的重要组成部分。
作者回顾了近期进展,并分享了她个人在描述数字乳腺摄影、计算机辅助检测、专用磁共振成像(MRI)以及正电子发射乳腺摄影在乳腺评估方面的现状的经验。
在50岁以下女性及乳腺致密的女性中,全视野数字乳腺摄影优于标准乳腺摄影。计算机辅助检测有助于经验不足的乳腺造影技师,并能提高致密乳腺中微钙化的检测率。乳腺MRI在术前评估、不明乳腺X线摄影的澄清以及BRCA突变携带者的随访中很有用。然而,MRI的特异性仍然存在问题。正电子发射乳腺摄影有望提高原位导管癌(DCIS)的检测率,即使其不伴有微钙化,并且应有助于手术规划。
乳腺成像的这四项重大进展均提高了乳腺异常检测的敏感性。然而,成本问题可能会限制这些进展的广泛应用。